Screening of either Higher Binding Affinity or Non-affinity scFv against Wild-type or Beta SARS-CoV-2. by Ye Yang (297214)

Identification, Synthesis, and Biological Evaluations of Potent Inhibitors Targeting Type I Protein Arginine Methyltransferases by Xiao Li (107004)

“…CARM1 (coactivator-associated arginine methyltransferase 1), which belongs to type I PRMTs (protein arginine methyltransferases), is a potential therapeutic target for treatment of multiple cancers. In this study, we first identified several hit compounds against CARM1 by structure-based virtual screening (IC₅₀ = 35.51 ± 6.68 to 68.70 ± 8.12 μM) and then carried out chemical structural optimizations, leading to six compounds with significantly improved activities targeting CARM1 (IC₅₀ = 18 ± 2 to 107 ± 6 nM). …”

Variable included in analysis. by Molebatsi Moholola (20513371)

“…</p><p>Results</p><p>Our final study sample consisted of 3 256 clients, half of which received case management (N = 1 628), 1084 (33%) with a first VL in study of 50–399 copies/ml, 404 (12%) 400–999 copies/ml and 1768 (54%) >1000 copies/ml. …”

Full dataset of the study. by Molebatsi Moholola (20513371)

“…</p><p>Results</p><p>Our final study sample consisted of 3 256 clients, half of which received case management (N = 1 628), 1084 (33%) with a first VL in study of 50–399 copies/ml, 404 (12%) 400–999 copies/ml and 1768 (54%) >1000 copies/ml. …”

Acquisition of Mutant scFv With a Higher Affinity against Wild-type, Beta and Delta SARS-CoV-2 using a HEK 293T Antibody Surface Display Library. by Ye Yang (297214)

The relative difference between the target dose of plan S₅₀ and base plan (n by Huaqu Zeng (20601563)

Deformation of buried DN50 PE pipeline exposed to 5000 kN/m² stacking load with various buried depths. by Pengcheng Li (123281)

Preclinical Evaluation of ¹³¹I/¹⁸F‑Labeled Covalent Small-Molecule Inhibitors for STING Status Imaging by Jianyang Fang (11301298)

Subjects:

Preclinical Evaluation of ¹³¹I/¹⁸F‑Labeled Covalent Small-Molecule Inhibitors for STING Status Imaging by Jianyang Fang (11301298)

Subjects:

Average number of consultations per day and per full-time equivalent occupational healthcare worker by year, and comparisons between years (Hedge’s bias corrected effect size and i... by Luther Dogbla (21410142)

Multi-way sensitivity analysis on transmission rate, CD4 count at diagnosis, and ART costs in a model-based analysis of Immediate ART initiation in Côte d’Ivoire. by Eric N. Ouattara (6890174)

Cost-effectiveness and budget impact of immediate antiretroviral therapy initiation for treatment of HIV infection in Côte d’Ivoire: A model-based analysis by Eric N. Ouattara (6890174)

Table_2_“If you weren't connected to the Internet, you were not alive”: experience of using social technology during COVID-19 in adults 50+.DOCX by Katrina Ling (13981107)

Table_1_“If you weren't connected to the Internet, you were not alive”: experience of using social technology during COVID-19 in adults 50+.DOCX by Katrina Ling (13981107)

Fitting curve of rock E₅₀. by Junxia Zhou (14381598)

Data Sheet 1_Reduced hemolytic complement activity in the classical pathway (CH50) is a risk factor for poor clinical outcomes of patients with infections: a retrospective analysis... by Hiroyuki Koami (3878434)

“…We divided the patients into three groups based on the normal CH50 range: Low CH50 (< 25 U/mL; n=168), Normal CH50 (25 ≤, < 48 U/mL; n=1273), and High CH50 (48 ≤ U/mL; n=1285).…”

Top 50 results of a commercial kinase screen using [γ³³]-ATP and human obscurin SH3-DH as substrates. by Daniel Koch (388049)

“…While MST2 addition resulted in strong and saturable phosphorylation, TBK1 led to much lower phosphorylation levels and CaMK4 addition led to an intermediate phosphorylation level exhibiting a biphasic behaviour with phosphorylation levels decreasing at higher substrate concentrations. Since MST2 showed the highest phosphorylation levels of obscurin SH3-DH, we focused on MST2 phosphorylation in all further experiments. …”

Transferrin Receptor-Mediated Cellular Uptake of Fluorinated Chlorido[<i>N</i>,<i>N</i>′‑bis(salicylidene)-1,2-phenylenediamine]iron(III) Complexes by Astrid Dagmar Bernkop-Schnürch (17461895)

Subjects:

Baseline characteristics of study participants, (N = 73). by Wafa Y. Ahmed (20727327)

Reasons behind not performing reinfibulation, (N = 73). by Wafa Y. Ahmed (20727327)