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Fasting-Mimicking Diet Is Safe and Reshapes Metabolism and Antitumor Immunity in Patients with Cancer
Published 2022“…<p dir="ltr">In tumor-bearing mice, cyclic fasting or fasting-mimicking diets (FMD) enhance the activity of antineoplastic treatments by modulating systemic metabolism and boosting antitumor immunity. Here we conducted a clinical trial to investigate the safety and biological effects of cyclic, five-day FMD in combination with standard antitumor therapies. …”
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143
Excess pCO<sub>2</sub> and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf)
Published 2022“…The tracer Alk*, defined as the deviation of potential alkalinity (A<sub>P</sub>) (where A<sub>P</sub> = TA + 1<b>.…”
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Efficacy and safety of using Etelcalcetide for controlling secondary hyperparathyroidism
Published 2024“…</p><h3>Results</h3><p dir="ltr">Patients within the PTH target range of 150 to 500pg/ml improved from 8% in June 2021 (on Cinacalcet) to 54% in June 2023 (on Etelcalcetide) (p=0 .0032) while patients with PTH above 1,000pg/ml decreased from 50% to 4% during the same period (p=0.00001) (Figure 2). …”
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Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000–17
Published 2020“…For piped water, the safest water facility type, access increased from 40·0% (95% uncertainty interval [UI] 39·4–40·7) to 50·3% (50·0–50·5), but was lowest in sub-Saharan Africa, where access to piped water was mostly concentrated in urban centres. …”
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Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation
Published 2025“…Compound 2a activated PPARγ with an EC50 value of 3.4 μM in a Gal4-hybrid reporter gene assay, indicating partial agonistic action. …”
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147
Impact of composition and salinity on swelling and gel strength of poly (acrylamide-co-acrylic acid) preformed particle gel
Published 2023“…<p dir="ltr">The effects of various material compositions and reservoir environments on the ultimate strength and swelling kinetics of a commercial preformed particle gel (PPG) have been investigated. …”
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Technical assessment of different extraction methods and transcriptome profiling of RNA isolated from small volumes of blood
Published 2023“…We have used the QuantSeq 3′ FWD mRNA-Seq Library Prep kit to prepare RNA-seq libraries, which were sequenced on the Illumina NextSeq 500 system. …”
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149
Postmicturition dribble in men with no previous urogenital surgery: Systematic review and meta‐analysis of treatment modalities
Published 2023“…Meta‐analyses of the two PDE5 inhibitors studies showed a large effect size with high heterogeneity for decreased PMD volume favoring PDE5 inhibitors over placebo (g = −0.86, 95% confidence interval [CI] −1.75; 0.02, p = 0.05; I2 = 88%); and a significant improvement equivalent to −1.06 points on the Hallym PMD Questionnaire score with no discernable heterogeneity (95% CI −1.65; −0.47, p = 0.0004; I2 = 0%), favoring PDE5 inhibitors compared to controls.…”
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Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway
Published 2022“…We established steatotic HepG2 cells by incubating the cells with 400 µM oleic acid (OA) overnight. …”
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miRNA-dependent regulation of STIM1 expression in breast cancer
Published 2019“…The ER Ca<sup>2+</sup> sensor STIM1 and Orai plasma membrane Ca<sup>2+</sup> channels molecularly mediate SOCE. Here we investigate the role of the microRNA machinery in regulating STIM1 expression. …”
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152
Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation
Published 2025“…Compound 2a activated PPARγ with an EC<sub>50</sub> value of 3.4 μM in a Gal4-hybrid reporter gene assay, indicating partial agonistic action. …”
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The effect of type and combination of fertilizers on eukaryotic microbiome of date palm rhizosphere
Published 2024“…<p dir="ltr">The date palm (<i>Phoenix dactylifera</i>) is an important cultivated crop in arid areas. Here, we studied the effect of plant genotype and type of fertilizers on the eukaryotic community structures of the date palm rhizosphere. …”
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Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery
Published 2019“…Following multiple comparison adjustment, changes in seven microRNAs remained significant: miR-7-5p, let-7f-5p, miR-15b-5p, let-7i-5p, miR-320c, miR-205-5p, and miR-335-5p. …”
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Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Diseas...
Published 2021“…We also compared these trends to those of smoked tobacco over the same time period. …”
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Effect of sintering temperature of NBT–6BT lead-free ceramics on the structural, ferroelectric and piezoelectric properties
Published 2022“…It is found that the optimal ferroelectric and piezoelectric values were obtained at 1150 °C (P r = 27 µC/cm 2 , E c = 3.89 kV/mm and d 33 = 110 pC/N). According to these results, we suggest that 850 °C and 1150 °C can be considered as optimal calcination and sintering temperature in NBT-6BT ceramic, respectively.…”
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Synthesis of lithium manganese oxide nanocomposites using microwave‐assisted chemical precipitation technique and their performance evaluation in lithium‐ion batteries
Published 2023“…Cycling efficiency is also improved, with LMO-CNTs and LMO-GNPs having an initial capacity of 124 and 127 mAhg<sup>−1</sup> decreasing to 112 and 114 mAhg<sup>−1</sup>, respectively, after 50 cycles. …”
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Role of Edge Groups in Defining the Stability of Aromatic Molecules Under Electron Irradiation
Published 2024“…<p dir="ltr">Electron irradiation is known to be an important physical tool in tuning the properties of self-assembled organic molecules. Here, we use X-ray photoelectron spectroscopy (XPS) measurements to study the effect of electron bombardment on the structural properties of dithiol aromatic molecules, where the sulfur atoms are either in direct conjugation with phenyl rings (case of Biphenyl-4,4′-dithiol, BPN) or separated by a methylene group (case of 5,5′-bis(mercaptomethyl)-2,2′-bipyridine, BPD). …”
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The global, regional, and national burden of stomach cancer in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease study 2017
Published 2020“…Globally, 38·2% (21·1–57·8) of the age-standardised DALYs were attributable to high-sodium diet in both sexes combined, and 24·5% (20·0–28·9) of the age-standardised DALYs were attributable to smoking in males. …”