Correlation of CD3+ infiltration and chemokines/cytokines. by Gerik W. Tushoski-Alemán (17951809)

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Dataset of patient cohort, CD3+ and CD8+ lymphocyte quantification, and inflammatory assay. by Gerik W. Tushoski-Alemán (17951809)

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Quantification of intratumoral CD3+ and CD8+ lymphocytes. by Gerik W. Tushoski-Alemán (17951809)

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Comparison of semi-quantitative and quantitative assessments of CD3+ and CD8+ lymphocytes in association with overall survival. by Gerik W. Tushoski-Alemán (17951809)

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The decrease or inhibition of Hsp90 induced REST degradation. by Raúl Orozco-Díaz (7067624)

“…(D) The level of REST dramatically reduced in differentiated SH-SY5Y cells treated with GA (1 μM) or PU-H71 (50 nM) at 24 h. (E) The REST level decreased by GA more than 50% and (F) PU-H71 more than 80%, respectively. …”

Germ cell size decreases before corpse formation. by Tea Kohlbrenner (19476160)

Discovery of Novel Substituted <i>N</i>‑(4-Amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide Analogues as Potent Human Adenovirus Inhibitors by Jimin Xu (2208961)

“…Notably, among these derivatives, compound <b>15</b> showed improved anti-HAdV activity (IC₅₀ = 0.27 μM), significantly decreased cytotoxicity (CC₅₀ = 156.8 μM), and low <i>in vivo</i> toxicity (maximum tolerated dose = 150 mg/kg in hamster) as compared with niclosamide, supporting its further <i>in vivo</i> efficacy studies for the treatment of HAdV infections.…”

Elevated IDO activity in HD mouse brains is decreased by <i>ex-vivo</i> iron chelation. by David W. Donley (3111198)

“…</b> Striatal IDO activity is increased in N171-82Q HD mice and significantly decreased by <i>ex vivo</i> iron (III) chelation (50 μM deferoxamine). …”

The aging-induced decrease in the number of dendritic branches in neurons of the hippocampus and cerebral cortex was attenuated by the administration of GTDE. by Hui-Chuan Kuo (12368492)

TTLL12 knockdown in HEp-2 and DU145 cells decreases cell survival in the presence of nitrotyrosine. by Amit Deshpande (255211)

Transferrin Receptor-Mediated Cellular Uptake of Fluorinated Chlorido[<i>N</i>,<i>N</i>′‑bis(salicylidene)-1,2-phenylenediamine]iron(III) Complexes by Astrid Dagmar Bernkop-Schnürch (17461895)

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Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects by Jie Zhou (28945)

“…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC₅₀ values of 10^–8 M. Among them, compound <b>80</b> (IC₅₀ = 0.07 μM, selectivity >130 fold over other K⁺, Na⁺, and Ca²⁺ ion channels) was able to decrease the apoptosis of HEK293/Kv2.1 cells induced by H₂O₂. …”

Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects by Jie Zhou (28945)

“…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC₅₀ values of 10^–8 M. Among them, compound <b>80</b> (IC₅₀ = 0.07 μM, selectivity >130 fold over other K⁺, Na⁺, and Ca²⁺ ion channels) was able to decrease the apoptosis of HEK293/Kv2.1 cells induced by H₂O₂. …”

Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects by Jie Zhou (28945)

“…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC₅₀ values of 10^–8 M. Among them, compound <b>80</b> (IC₅₀ = 0.07 μM, selectivity >130 fold over other K⁺, Na⁺, and Ca²⁺ ion channels) was able to decrease the apoptosis of HEK293/Kv2.1 cells induced by H₂O₂. …”

1466 slows the capsid assembly rate in biochemical Cp149 capsid assembly reactions. by Daniel P. Bradley (10306893)

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1466 inhibits capsid accumulation independent of HBV replication. by Daniel P. Bradley (10306893)

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Compound 390 induces HBV capsid accumulation via an ROS-mediated mechanism. by Daniel P. Bradley (10306893)

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HPD compounds 1736 and 1740 also suppress accumulation of HBV capsids. by Daniel P. Bradley (10306893)

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1466 does not induce disassembly of pre-formed HBV capsids in cell lysates. by Daniel P. Bradley (10306893)

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Nanodomains and Their Temperature Dependence in a Phosphonium-Based Ionic Liquid: A Single-Molecule Tracking Study by Jemima Opare-Addo (14657955)

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