بدائل البحث:
nn decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), mean decrease (توسيع البحث)
na decrease » a decrease (توسيع البحث), pa decreased (توسيع البحث), la decreased (توسيع البحث)
n decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), _ decreased (توسيع البحث)
50 nn » 50 ns (توسيع البحث), 50 ng (توسيع البحث), 59 nn (توسيع البحث)
50 na » 50 ns (توسيع البحث), 50 ng (توسيع البحث), 40 na (توسيع البحث)
50 n » 50 ns (توسيع البحث), 50 ng (توسيع البحث), 50 μ (توسيع البحث)
nn decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), mean decrease (توسيع البحث)
na decrease » a decrease (توسيع البحث), pa decreased (توسيع البحث), la decreased (توسيع البحث)
n decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), _ decreased (توسيع البحث)
50 nn » 50 ns (توسيع البحث), 50 ng (توسيع البحث), 59 nn (توسيع البحث)
50 na » 50 ns (توسيع البحث), 50 ng (توسيع البحث), 40 na (توسيع البحث)
50 n » 50 ns (توسيع البحث), 50 ng (توسيع البحث), 50 μ (توسيع البحث)
-
121
-
122
-
123
-
124
-
125
Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects
منشور في 2023"…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC<sub>50</sub> values of 10<sup>–8</sup> M. Among them, compound <b>80</b> (IC<sub>50</sub> = 0.07 μM, selectivity >130 fold over other K<sup>+</sup>, Na<sup>+</sup>, and Ca<sup>2+</sup> ion channels) was able to decrease the apoptosis of HEK293/Kv2.1 cells induced by H<sub>2</sub>O<sub>2</sub>. …"
-
126
Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects
منشور في 2023"…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC<sub>50</sub> values of 10<sup>–8</sup> M. Among them, compound <b>80</b> (IC<sub>50</sub> = 0.07 μM, selectivity >130 fold over other K<sup>+</sup>, Na<sup>+</sup>, and Ca<sup>2+</sup> ion channels) was able to decrease the apoptosis of HEK293/Kv2.1 cells induced by H<sub>2</sub>O<sub>2</sub>. …"
-
127
Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects
منشور في 2023"…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC<sub>50</sub> values of 10<sup>–8</sup> M. Among them, compound <b>80</b> (IC<sub>50</sub> = 0.07 μM, selectivity >130 fold over other K<sup>+</sup>, Na<sup>+</sup>, and Ca<sup>2+</sup> ion channels) was able to decrease the apoptosis of HEK293/Kv2.1 cells induced by H<sub>2</sub>O<sub>2</sub>. …"
-
128
-
129
-
130
-
131
-
132
Expanding Three-Coordinate Gold(I) Anticancer Agent Chemical Space
منشور في 2025"…The complexes demonstrated submicromolar cytotoxic activity against human breast cancer cells MDA-MB-231 or MDA-MB-468 with IC<sub>50</sub>’s in the range of 0.4–5.0 μM. Complex <b>2e</b> shows high potency in vitro and decreases 3D-breast cancer mammosphere viability. …"
-
133
-
134
-
135
-
136
-
137
-
138
-
139
-
140
1466 does not change total yield of capsids during biochemical assembly reactions.
منشور في 2025الموضوعات: