Showing 161 - 180 results of 6,264 for search '(((( 50 nn decrease ) OR ( 50 ng decrease ))) OR ((( 50 n decrease ) OR ( 50 μs decrease ))))', query time: 0.85s Refine Results
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    Antimicrobial activity of RP-1 peptide conjugate with ferrocene group by Natalia C. S. Costa (8626206)

    Published 2020
    “…The Fc-RP1 presented anti-amastigote activity against <i>Leishmania amazonensis</i> (IC<sub>50</sub> = 0.25 μmol L<sup>–1</sup>). In comparison with amphotericin B, a second-line drug approved for leishmaniasis treatment, (IC<sub>50</sub> = 0.63 μmol L<sup>-1</sup>), Fc-RP1 was more active and showed a 2.5-fold higher selectivity index. …”
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    Decreased virulence observed during <i>in planta</i> infection with <i>ΔFgknr4</i>. by Erika Kroll (20537020)

    Published 2025
    “…Scale bar = 50 μm. <b>E.</b> Wheat spike infection complementation assay done on the susceptible cultivar Bobwhite treated with conidia either from wild-type <i>F</i>. …”
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    Fig 5 - by Shivankar Agrawal (11565095)

    Published 2021
    Subjects:
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    Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects by Jie Zhou (28945)

    Published 2023
    “…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC<sub>50</sub> values of 10<sup>–8</sup> M. Among them, compound <b>80</b> (IC<sub>50</sub> = 0.07 μM, selectivity >130 fold over other K<sup>+</sup>, Na<sup>+</sup>, and Ca<sup>2+</sup> ion channels) was able to decrease the apoptosis of HEK293/Kv2.1 cells induced by H<sub>2</sub>O<sub>2</sub>. …”
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    Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects by Jie Zhou (28945)

    Published 2023
    “…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC<sub>50</sub> values of 10<sup>–8</sup> M. Among them, compound <b>80</b> (IC<sub>50</sub> = 0.07 μM, selectivity >130 fold over other K<sup>+</sup>, Na<sup>+</sup>, and Ca<sup>2+</sup> ion channels) was able to decrease the apoptosis of HEK293/Kv2.1 cells induced by H<sub>2</sub>O<sub>2</sub>. …”
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    Discovery of 2‑Ethoxy-5-isobutyramido‑<i>N</i>‑1-substituted Benzamide Derivatives as Selective Kv2.1 Inhibitors with In Vivo Neuroprotective Effects by Jie Zhou (28945)

    Published 2023
    “…In this work, a series of novel benzamide derivatives were designed and synthesized as Kv2.1 inhibitors, and extensive structure–activity relationships led to highly potent and selective Kv2.1 inhibitors having IC<sub>50</sub> values of 10<sup>–8</sup> M. Among them, compound <b>80</b> (IC<sub>50</sub> = 0.07 μM, selectivity >130 fold over other K<sup>+</sup>, Na<sup>+</sup>, and Ca<sup>2+</sup> ion channels) was able to decrease the apoptosis of HEK293/Kv2.1 cells induced by H<sub>2</sub>O<sub>2</sub>. …”
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    Discovery of <i>N</i>‑(1,3,4-Thiadiazol-2-yl)amide Derivatives as Uncompetitive Inhibitors of 6‑Phosphogluconate Dehydrogenase by Rong Zhang (44942)

    Published 2025
    “…Among them, <b>19n</b> exhibited significant potency against 6PGD with an IC<sub>50</sub> value of 5.1 ± 1.0 μM. …”
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    Inhibiting Gamma-secretase activity without interfering in Notch signaling: Decreasing the inflammatory response in patients with cutaneous leishmaniasis by Lucas Carvalho (3093042)

    Published 2020
    “…</b>PBMC from CL patients (n=12) were cultured in presence or absence of SLA (5ug/mL) and DAPT (20µM) for 72 hours. …”
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