First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation حسب Kairui Yue (11874403)

"…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …"

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation حسب Kairui Yue (11874403)

"…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …"

Biocompatible and Antifouling Linear Poly(<i>N</i>‑(2-hydroxypropyl)methacrylamide)-Coated Capillaries via Aqueous RAFT Polymerization Method for Clinical Proteomics Analysis of No... حسب Mengqing Yang (13253917)

Data_Sheet_1_Marathon Running Increases Synthesis and Decreases Catabolism of Joint Cartilage Type II Collagen Accompanied by High-Energy Demands and an Inflamatory Reaction.PDF حسب José A. Hernández-Hermoso (11545663)

"…Mean sC2C levels (220.83 ± 39.50 ng/ml) decreased post-race (188.67 ± 38.52 ng/ml) (p = 0.002). …"

Assessment of cell proliferation within the vocal fold muscle following DFATs transplantation. حسب Ikuo Mikoshiba (9312007)

Association between predictor variables and development of neurological complications among COVID-19 patients. حسب Javaria Aslam (13864104)

Fig 9 - حسب Dennis Ochola (11626912)

Fig 7 - حسب Dennis Ochola (11626912)

Fig 4 - حسب Dennis Ochola (11626912)

Fig 5 - حسب Dennis Ochola (11626912)

Supplementary Material for: Adjunctive active vitamin D (AVD) decreases kidney function during treatment of secondary hyperparathyroidism (SHPT) with extended-release calcifediol (... حسب figshare admin karger (2628495)

Relative change and 95% confidence intervals in overall, urogenital, anorectal and oropharyngeal chlamydia and gonorrhoea testing among GPs in Amsterdam after participation in an e... حسب Saskia Bogers (14322197)

Maternal Transfer of 2‑Ethylhexyl Diphenyl Phosphate Leads to Developmental Toxicity Possibly by Blocking the Retinoic Acid Receptor and Retinoic X Receptor in Japanese Medaka (Ory... حسب Yu Li (183836)

"…After adult female medaka were exposed to EHDPP at 156, 405, and 1161 ng/L for 35 days, the embryonic EHDPP concentrations (364–4824 ng/g lipid weight (lw)) were higher than those in the maternal tissues (15.0–4166 ng/g lw), showing notable maternal transfer. …"

Inhibition of pan- and HDAC isoform activities. حسب Mira Jung (1277502)

"…Pharmacokinetic evaluation demonstrates an area under the curve (AUC) of 5227.55 ng/ml × h with an elimination half-life of 1.26 h following intravenous administration in a rat model. …"

Data Sheet 1_Effect of threonine level in a high-protein diet on the growth performance and carcass characteristics of 50- to 91-day-old slow-growing indigenous male Boschveld chic... حسب Tebogo Mack Sekgotodi (22465483)

Antibodies used for flow cytometry experiments. حسب Joseph Rabin (7399436)

"…RA was devoid of serious side effects, and within 24 hours from the start of infusion was associated with increased oxygen saturation (93.8 ± 0.58 vs 96.6 ± 1.08%, P<0.05), decreased D-dimer (754 ± 17 vs 518 ± 98 ng/ml, P<0.05), and a trend toward decreased CRP (3.80 ± 1.40 vs 1.98 ± 0.74 mg/dL, P = 0.075). …"

Subject flow diagram. حسب Joseph Rabin (7399436)

"…RA was devoid of serious side effects, and within 24 hours from the start of infusion was associated with increased oxygen saturation (93.8 ± 0.58 vs 96.6 ± 1.08%, P<0.05), decreased D-dimer (754 ± 17 vs 518 ± 98 ng/ml, P<0.05), and a trend toward decreased CRP (3.80 ± 1.40 vs 1.98 ± 0.74 mg/dL, P = 0.075). …"

Size distributions of ucfDNA molecules. حسب Meihui Chen (1670020)

Analysis of ucfDNA in DHSs between control and age-comparable bladder cancer groups. حسب Meihui Chen (1670020)

Effects of TGF-β1 on the expression of fibrosis indicators in HBdSMCs and the effects of MEL on the expression of fibrosis indicators in HBdSMCs induced by TGF-β1. حسب Yang Zhang (30734)