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Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation
منشور في 2025"…As well, the expression levels of 20-HETE, Il-1β and TNF-α were decreased in LPS-challenged RAW264.7 macrophages upon treatment with compound <b>2a</b>. …"
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Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells
منشور في 2021"…Pt/MgO nanoparticles were cuboid and in the nanosize range of 30–50 nm. The cytotoxicity of Pt/MgO nanoparticles was determined via the 3-(4,5-dimethylthiazol-2-yl)−2,5-diphenyltetrazolium bromide assay on the human lung and colonic cancer cells (A549 and HT29 respectively) and normal human lung and colonic fibroblasts cells (MRC-5 and CCD-18Co repectively). …"
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Dynamic Change in Insulin Resistance Induced by Free Fatty Acids Is Unchanged Though Insulin Sensitivity Improves Following Endurance Exercise in PCOS
منشور في 2018"…The glucose disposal rate during the lipid infusion was reduced following exercise in PCOS, indicating decreased IR (67 ± 5 vs. 50 ± 7%, p = 0.02), but IR was not altered in controls (49 ± 7 vs. 45 ± 6%, p = 0.58). …"
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Fixed Shading Scenarios to Optimize Lighting Performance and Energy Efficiency in Office Buildings Case Study of Dubai Design District
منشور في 2021"…The second-best method was the Horizontal Louvers, where it achieved a reduction in energy consumption by 7.7% compared to the base case, and in daylight, it achieved a decrease of 50% in Both selected months. …"
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Novel paclitaxel formulations solubilized by parenteral nutrition nanoemulsions for application against glioma cell lines
منشور في 2016"…The pH range for the Clinoleic formulations (7.1–7.5) was slightly higher than that of the Intralipid formulations (6.5–6.9). …"
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168
Excess pCO2 and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf)
منشور في 2022"…Its values in the Gulf ranged from −50 to −310 μmol kg−1 implying CaCO3 precipitation. …"
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169
An additive manufacturing approach based on electrohydrodynamic printing to fabricate P3HT:PCBM thin films
منشور في 2023"…The root-mean-square roughness was found to vary significantly with the annealing temperature and the flow rate and ranged from 1.938 to 3.345 nm. The estimated film mass and thickness were found between 3.235 and 23.471 mg and 597.5 nm to 1.60 µm, respectively. …"
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Effect of anions on the structural, morphological and dielectric properties of hydrothermally synthesized hydroxyapatite nanoparticles
منشور في 2019"…For the particles obtained from nitrate, acetate, chloride and egg shell precursors respectively give dielectric constant (εʹ) values of 9.96, 13.22, 9.92 and 10.86 at 5 MHz. The εʹ and dielectric loss (εʹʹ) values for the HA nanoparticles decrease with increase in the applied frequency as well. …"
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Crumpled MXene nanosheets for sensing of ascorbic acid in food, biological fluids, and erythrocytes in-vitro microenvironment
منشور في 2023"…The sensor also demonstrated excellent reproducibility (~1 % RSD for five repetitive assays) and a shelf life of nearly one month with a negligible decrease in response. …"
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Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity
منشور في 2023"…</p> <p>Results: The BCAA-restricted diet significantly reduced circulating BCAA concentrations by ~50% i.e., baseline 437 ± 60 to 217 ± 40 µmol/L (p < 0.005). …"
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Strengthening of thin reinforced concrete slabs with CFRP laminates
منشور في 2016"…Two groups of slab specimens having a thickness of 75 mm were cast with a concrete compressive strength of 50 MPa and 100 MPa, respectively. …"
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174
Nanospace-engineered carbons for reversible storage of natural gas and hydrogen
منشور في 2011"…Excess adsorption dominated by KOH:C ratio. 2.Volumetric storage capacity decreases with increasing activation temperature. 3. 2.5K activated at 700 oC has record volumetric storage capacity of 132 g CH4/liter carbon at 35 bar and 22 oC (200 V/V, 110% of DOE target of 118 g/liter). …"
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175
SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs
منشور في 2019"…The <i>K</i><sub><em>i</em></sub> values of compound 16 were determined to be 0.047 and 0.020 μM for the inhibition of MAO-A and MAO-B, respectively. …"
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Potent anti-tumor promoting effects of Daucus carota oil extract in mice
منشور في 2008"…Tumor volume was decreased by 99, 91 and 70% following topical treatments with 100, 50 and 5% oil extract respectively. …"
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177
Biodegradable polysaccharide grafted polyacrylamide inhibitor for corrosion in CO<sub>2</sub>- saturated saline solution
منشور في 2023"…Lastly, potentiostatic testing of steel with AGGPAM at an applied potential of 50 mV illustrated surface protection and decreased current over a prolonged time. …"
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Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy
منشور في 2019"…We also found increased levels of LAMP-1 and LAMP-2A both <i>in vitro</i> and <i>in vivo</i>, along with decreased levels of α-synuclein. …"
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