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Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation
Published 2025“…As well, the expression levels of 20-HETE, Il-1β and TNF-α were decreased in LPS-challenged RAW264.7 macrophages upon treatment with compound <b>2a</b>. …”
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162
Dynamic Change in Insulin Resistance Induced by Free Fatty Acids Is Unchanged Though Insulin Sensitivity Improves Following Endurance Exercise in PCOS
Published 2018“…The glucose disposal rate during the lipid infusion was reduced following exercise in PCOS, indicating decreased IR (67 ± 5 vs. 50 ± 7%, p = 0.02), but IR was not altered in controls (49 ± 7 vs. 45 ± 6%, p = 0.58). …”
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163
Fixed Shading Scenarios to Optimize Lighting Performance and Energy Efficiency in Office Buildings Case Study of Dubai Design District
Published 2021“…The second-best method was the Horizontal Louvers, where it achieved a reduction in energy consumption by 7.7% compared to the base case, and in daylight, it achieved a decrease of 50% in Both selected months. …”
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164
Improved properties and salt rejection of polysulfone membrane by incorporation of hydrophilic cobalt-doped ZnO nanoparticles
Published 2024“…The hybrid PSf membranes were fabricated with 0.5 wt. % of ZnO and doped ZnO NPs. These membranes were characterized using XRD, TGA, FESEM-EDX, and salt rejection performance. …”
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Enhanced thermoelectric properties of Bi<sub>2</sub>Te<sub>2.55</sub>Se<sub>0.45</sub> nanocomposites using eco-friendly Eocene Midra Shale palygorskite nanofillers: A sustainable...
Published 2025“…The EMS was obtained from one of Qatar’s substantial hydrocarbon reservoirs and mixed with the Bi2Te2.55Se0.45 alloy using ball-milling and hot-pressing techniques. Different wt% of EMS (0.025, 0.05, 0.1, 0.5, and 1) were considered. …”
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167
Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity
Published 2023“…</p> <p>Results: The BCAA-restricted diet significantly reduced circulating BCAA concentrations by ~50% i.e., baseline 437 ± 60 to 217 ± 40 µmol/L (p < 0.005). …”
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168
Strengthening of thin reinforced concrete slabs with CFRP laminates
Published 2016“…Two groups of slab specimens having a thickness of 75 mm were cast with a concrete compressive strength of 50 MPa and 100 MPa, respectively. …”
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169
SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs
Published 2019“…The <i>K</i><sub><em>i</em></sub> values of compound 16 were determined to be 0.047 and 0.020 μM for the inhibition of MAO-A and MAO-B, respectively. …”
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170
Potent anti-tumor promoting effects of Daucus carota oil extract in mice
Published 2008“…Tumor volume was decreased by 99, 91 and 70% following topical treatments with 100, 50 and 5% oil extract respectively. …”
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171
Trace element composition of size-fractionated suspended particulate matter samples from the Qatari Exclusive Economic Zone of the Arabian Gulf: the role of atmospheric dust
Published 2020“…Size-fractionated suspended particles were collected using net tows with mesh sizes of 50 and 200 µm to examine the composition of small- and large-size plankton populations. …”
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Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy
Published 2019“…We also found increased levels of LAMP-1 and LAMP-2A both <i>in vitro</i> and <i>in vivo</i>, along with decreased levels of α-synuclein. …”
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Impact of composition and salinity on swelling and gel strength of poly (acrylamide-co-acrylic acid) preformed particle gel
Published 2023“…The swelling ratios of the PPGs in brine 1 at 50 °C were between 12 and 32 g/g, having strengths in the range of 566–5508 Pa, depending on the crosslinker ratio. …”
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176
Detailed organic characterization of process water to evaluate reverse osmosis membrane fouling in industrial wastewater treatment
Published 2024“…After ACF treatment, the hydrophobic organics decreased to 0.65 mg/L, revealing that the ACF is removing >50 % of hydrophobic organics which are likely responsible for membrane fouling. …”
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177
Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation
Published 2025“…As well, the expression levels of 20-HETE, Il-1β and TNF-α were decreased in LPS-challenged RAW264.7 macrophages upon treatment with compound 2a. …”
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Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis
Published 2025“…</p><h3>Results</h3><p dir="ltr">LAT2KO mice experienced a notable reduction in body weight during fasting (WT:14% and LAT2KO:18%, <i>p</i> = 0.02), with a greater reduction in fat mass (0.5‐fold, <i>p</i> = 0.013) and a higher relative retention of muscle mass (1.3‐fold, <i>p</i> = 0.0003) compared with WT. …”