بدائل البحث:
ppm decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), nn decrease (توسيع البحث)
ns decrease » nn decrease (توسيع البحث), _ decrease (توسيع البحث), a decrease (توسيع البحث)
we decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), nn decrease (توسيع البحث)
μ decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), _ decreased (توسيع البحث)
50 ppm » 5 ppm (توسيع البحث)
ppm decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), nn decrease (توسيع البحث)
ns decrease » nn decrease (توسيع البحث), _ decrease (توسيع البحث), a decrease (توسيع البحث)
we decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), nn decrease (توسيع البحث)
μ decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), _ decreased (توسيع البحث)
50 ppm » 5 ppm (توسيع البحث)
-
21
-
22
-
23
-
24
-
25
-
26
-
27
-
28
-
29
Discovery of New Inhibitors of Hepatitis C Virus NS3/4A Protease and Its D168A Mutant
منشور في 2019"…However, in the same assay, the potency of the approved drug, simeprevir, decreased 5.7-fold for the mutant enzyme relative to the wild type. …"
-
30
-
31
-
32
-
33
-
34
-
35
Design of Benzyl-triazolopyrimidine-Based NADPH Oxidase Inhibitors Leads to the Discovery of a Potent Dual Covalent NOX2/MAOB Inhibitor
منشور في 2025"…We found that <b>9a</b>, bearing a pargyline moiety, is also able to selectively inhibit MAOB over MAOA (465-fold) with an IC<sub>50</sub> of 0.182 μM, being the first-in-class dual NOX2/MAOB covalent inhibitor. …"
-
36
Claudin V is decreased following infection with Mtb.
منشور في 2024"…Exposure to Mtb H37Rv and HN878 decreased claudin V expression compared to uninfected controls in the frontal cortex (E), cerebral nuclei (J), brain stem (O), thalamus (T), and hippocampus (Y). …"
-
37
-
38
Design, Synthesis, and Biological Evaluation of [1,2,5]Oxadiazolo[3,4‑<i>b</i>]pyridin-7-ol as Mitochondrial Uncouplers for the Treatment of Obesity and Metabolic Dysfunction-Assoc...
منشور في 2024"…Utilizing an oxygen consumption rate assay as a measure of increased cellular respiration, <b>SHO1122147</b> (<b>7m</b>) displayed an EC<sub>50</sub> of 3.6 μM in L6 myoblasts. Pharmacokinetic studies indicated a half-life of 2 h, <i>C</i><sub>max</sub> of 35 μM, and no observed adverse effects at 1,000 mg kg<sup>–1</sup> dose in mice. …"
-
39
-
40