يعرض 21 - 40 نتائج من 12,255 نتيجة بحث عن '(((( 50 ppm decrease ) OR ( 50 ((ns decrease) OR (we decrease)) ))) OR ( 5 μ decrease ))', وقت الاستعلام: 0.78s تنقيح النتائج
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    Discovery of New Inhibitors of Hepatitis C Virus NS3/4A Protease and Its D168A Mutant حسب Ittipat Meewan (7455041)

    منشور في 2019
    "…However, in the same assay, the potency of the approved drug, simeprevir, decreased 5.7-fold for the mutant enzyme relative to the wild type. …"
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    Fig 5 - حسب Lingru Ruan (18995544)

    منشور في 2024
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    Design of Benzyl-triazolopyrimidine-Based NADPH Oxidase Inhibitors Leads to the Discovery of a Potent Dual Covalent NOX2/MAOB Inhibitor حسب Beatrice Noce (16540800)

    منشور في 2025
    "…We found that <b>9a</b>, bearing a pargyline moiety, is also able to selectively inhibit MAOB over MAOA (465-fold) with an IC<sub>50</sub> of 0.182 μM, being the first-in-class dual NOX2/MAOB covalent inhibitor. …"
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    Claudin V is decreased following infection with Mtb. حسب Amanda S. Latham (12093638)

    منشور في 2024
    "…Exposure to Mtb H37Rv and HN878 decreased claudin V expression compared to uninfected controls in the frontal cortex (E), cerebral nuclei (J), brain stem (O), thalamus (T), and hippocampus (Y). …"
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    Design, Synthesis, and Biological Evaluation of [1,2,5]Oxadiazolo[3,4‑<i>b</i>]pyridin-7-ol as Mitochondrial Uncouplers for the Treatment of Obesity and Metabolic Dysfunction-Assoc... حسب Mary A. Foutz (20361830)

    منشور في 2024
    "…Utilizing an oxygen consumption rate assay as a measure of increased cellular respiration, <b>SHO1122147</b> (<b>7m</b>) displayed an EC<sub>50</sub> of 3.6 μM in L6 myoblasts. Pharmacokinetic studies indicated a half-life of 2 h, <i>C</i><sub>max</sub> of 35 μM, and no observed adverse effects at 1,000 mg kg<sup>–1</sup> dose in mice. …"
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