بدائل البحث:
ppm decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), pa decreased (توسيع البحث)
nn decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), mean decrease (توسيع البحث)
we decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), mean decrease (توسيع البحث)
c decrease » c decreased (توسيع البحث), _ decrease (توسيع البحث), a decrease (توسيع البحث)
50 ppm » 5 ppm (توسيع البحث)
50 nn » 50 ns (توسيع البحث), 50 ng (توسيع البحث), 50 n (توسيع البحث)
50 c » 5 c (توسيع البحث), 50 μ (توسيع البحث), 50 _ (توسيع البحث)
5 we » _ we (توسيع البحث), 5 wt (توسيع البحث), 5 w (توسيع البحث)
ppm decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), pa decreased (توسيع البحث)
nn decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), mean decrease (توسيع البحث)
we decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), mean decrease (توسيع البحث)
c decrease » c decreased (توسيع البحث), _ decrease (توسيع البحث), a decrease (توسيع البحث)
50 ppm » 5 ppm (توسيع البحث)
50 nn » 50 ns (توسيع البحث), 50 ng (توسيع البحث), 50 n (توسيع البحث)
50 c » 5 c (توسيع البحث), 50 μ (توسيع البحث), 50 _ (توسيع البحث)
5 we » _ we (توسيع البحث), 5 wt (توسيع البحث), 5 w (توسيع البحث)
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Expanding Three-Coordinate Gold(I) Anticancer Agent Chemical Space
منشور في 2025"…The complexes demonstrated submicromolar cytotoxic activity against human breast cancer cells MDA-MB-231 or MDA-MB-468 with IC<sub>50</sub>’s in the range of 0.4–5.0 μM. Complex <b>2e</b> shows high potency in vitro and decreases 3D-breast cancer mammosphere viability. …"
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Presentation_1_Eosinophils Decrease Pulmonary Metastatic Mammary Tumor Growth.pptx
منشور في 2022"…We found that IL5Tg mice exhibit reduced pulmonary metastatic colonization and decreased metastatic tumor burden compared to wild-type (WT) mice or eosinophil-deficient mice. …"
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Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance...
منشور في 2021"…Targeting P-glycoprotein (ABCB1 or P-gp) has been recognized as a promising strategy to overcome multidrug resistance. Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo[1,5-<i>a</i>]pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …"
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Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance...
منشور في 2021"…Targeting P-glycoprotein (ABCB1 or P-gp) has been recognized as a promising strategy to overcome multidrug resistance. Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo[1,5-<i>a</i>]pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …"
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Isolation of Grain versus Intergranular Transport in Li<sub>1+<i>x</i></sub>Ti<sub><i>x</i></sub>Ta<sub>1–<i>x</i></sub>SiO<sub>5</sub> Suggests Concerted Ion Migration in a High-V...
منشور في 2023"…The grain and intergranular conductivities were separated using electrochemical impedance spectroscopy with distribution of relaxation times analysis (EIS/DRT). We showed the first clear observation of a monotonic decrease in activation energy <i>E</i><sub>A</sub> from 0.50 to 0.29 eV and a 6× increase in Li<sup>+</sup> conductivity in the grains to 2.49 × 10<sup>–5</sup> S/cm for <i>x</i> = 0.15 (30 °C) as more Li<sub>i</sub><sup>•</sup> were inserted, providing insight into how Li<sub>i</sub><sup>•</sup> potentially triggered concerted transport. …"
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Isolation of Grain versus Intergranular Transport in Li<sub>1+<i>x</i></sub>Ti<sub><i>x</i></sub>Ta<sub>1–<i>x</i></sub>SiO<sub>5</sub> Suggests Concerted Ion Migration in a High-V...
منشور في 2023"…The grain and intergranular conductivities were separated using electrochemical impedance spectroscopy with distribution of relaxation times analysis (EIS/DRT). We showed the first clear observation of a monotonic decrease in activation energy <i>E</i><sub>A</sub> from 0.50 to 0.29 eV and a 6× increase in Li<sup>+</sup> conductivity in the grains to 2.49 × 10<sup>–5</sup> S/cm for <i>x</i> = 0.15 (30 °C) as more Li<sub>i</sub><sup>•</sup> were inserted, providing insight into how Li<sub>i</sub><sup>•</sup> potentially triggered concerted transport. …"
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Decreased phosphorylation of EIF2α underlies the impairment of arsenite-induced SG formation in LSM12-depleted cells.
منشور في 2020"…Control<sup>shRNA</sup> and <i>LSM12</i><sup>shRNA</sup> cells were incubated with 0.4-M sorbitol for the indicated time before co-staining with anti-ATXN2 antibody (red), anti-G3BP1 antibody (green), and Hoechst 33258 (blue). (B, C) LSM12 depletion decreases the arsenite-induced phosphorylation of EIF2α. …"
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The GluN2B-C456Y mutation decreases recombinant NMDAR currents and alters receptor properties.
منشور في 2020"…<p>(A) The GluN2B-C456Y mutation strongly decreases diheteromeric GluN1/GluN2B NMDAR currents in <i>Xenopus</i> oocytes. …"
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