Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

PI+ CD3+ T cells decrease at day 14 after IR while PI+ CD3- cells decrease at all time points. by Jordan A. Gunning (18143970)

Percentage decrease in model output peak with the administration of exogenous estrogen/progesterone. by Brenda Lyn A. Gavina (15285185)

Naringenin decreases total cell viability. by Lauren A. Eanes (20995499)

IFNγ enhances the Ser/5-HT-promoted <i>Trypanosoma cruzi</i> uptake by the human U-87 MG astroglioma cells. by Glaucia Vilar-Pereira (686134)

Fx treatment abrogates the Ser/5-HT-promoted <i>Trypanosoma cruzi</i> infection of human U-87 MG astroglioma cells. by Glaucia Vilar-Pereira (686134)

Cardamonin decreased the protein expression of lipogenic proteins. by Peiguang Niu (17044532)

RhoA gene expression and activity are impacted with increased intracellular 5HT. by Celeste M. Sheftel (9557588)

“…<p><b>A.</b><i>RhoA</i> mRNA expression is significantly upregulated with FLX and 5HTP compared to controls and is significantly decreased in FLX + MDC. …”

Inhibition of ABCG2 decreases SP cells, but not sphere-forming ability. by Noriko Kawai (6694010)

Mean and standard deviation of vascular density. by Beatriz Cordon (9745619)

Subjects:

Mean and standard deviation of vascular density. by Beatriz Cordon (9745619)

Subjects:

Mean and standard deviation of vascular density. by Beatriz Cordon (9745619)

Subjects:

Mean and standard deviation of vascular density. by Beatriz Cordon (9745619)

Subjects:

Mean platelet volume and neutrophil to lymphocyte ratio decrease in patients with depression with antidepressant treatment by AHMET ÖZTÜRK (8077292)

Design, Synthesis, and Biological Evaluation of New Peripheral 5HT_2A Antagonists for Nonalcoholic Fatty Liver Disease by Minhee Kim (1592440)

“…Here, structural modifications of pimavanserin (CNS drug), a 5HT_2A antagonist approved for Parkinson’s disease, led us to synthesize new peripherally acting 5HT_2A antagonists. …”

Data Sheet 1_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.pdf by Evan Fuini (21224939)

Table 4_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.xlsx by Evan Fuini (21224939)

Data Sheet 2_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.docx by Evan Fuini (21224939)

Table 1_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.docx by Evan Fuini (21224939)

Table 5_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.xlsx by Evan Fuini (21224939)