Showing 161 - 180 results of 145,812 for search '(((( 50 we decrease ) OR ( 50 c decrease ))) OR ( 10 ((a decrease) OR (nn decrease)) ))', query time: 1.00s Refine Results
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    Design of Benzyl-triazolopyrimidine-Based NADPH Oxidase Inhibitors Leads to the Discovery of a Potent Dual Covalent NOX2/MAOB Inhibitor by Beatrice Noce (16540800)

    Published 2025
    “…We found that <b>9a</b>, bearing a pargyline moiety, is also able to selectively inhibit MAOB over MAOA (465-fold) with an IC<sub>50</sub> of 0.182 μM, being the first-in-class dual NOX2/MAOB covalent inhibitor. …”
  3. 163

    Discovery of Triazolyl Derivatives of Cucurbitacin B Targeting IGF2BP1 against Non-Small Cell Lung Cancer by Fan-Fan Shang (16953264)

    Published 2023
    “…Among them, derivative <b>A11</b> had the most potent antiproliferative activity against A549 lung cancer cells (IC<sub>50</sub> = 0.009 μM) and was approximately 10-fold more potent than CuB, while the cytotoxicity of <b>A11</b> toward normal L02 cells was about 10-fold less potent, indicating a much wider therapeutic window than CuB. …”
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    Data_Sheet_1_Perceptual Priming Can Increase or Decrease With Aging.PDF by Kalathupiriyan A. Zhivago (9659504)

    Published 2020
    “…However, whether and how implicit perceptual memory varies with aging or cognitive impairment is unclear. Here, we compared implicit perceptual memory and explicit memory measures in three groups of participants: (1) 59 healthy young volunteers (20–30 years); (2) 269 healthy old volunteers (50–90 years) and (3) 21 patients with mild cognitive impairment, i.e., MCI (50–90 years). …”
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    Decreased phosphorylation of EIF2α underlies the impairment of arsenite-induced SG formation in LSM12-depleted cells. by Jongbo Lee (9914603)

    Published 2020
    “…All underlying numerical values are available in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3001002#pbio.3001002.s016" target="_blank">S1 Data</a>. …”
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    Juvenile demyelination leads to a substantial decrease in potassium currents in PV interneurons of the PFC. by Sara Hijazi (21656615)

    Published 2025
    “…Scale: 500 pA, 100 ms. <b>B</b>. I–V curves showing a significant decrease in Kv amplitude in PV interneurons from mice that underwent juvenile demyelination. …”
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    The GluN2B-C456Y mutation decreases recombinant NMDAR currents and alters receptor properties. by Wangyong Shin (6793040)

    Published 2020
    “…<p>(A) The GluN2B-C456Y mutation strongly decreases diheteromeric GluN1/GluN2B NMDAR currents in <i>Xenopus</i> oocytes. …”
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    Simulated effects of increased pCREB combined with decreased pCaMKIIα on bistability. by Yili Zhang (540283)

    Published 2022
    “…(C) Summary table. The steady states of variables 48 h after training with <i>k</i><sub><i>basalp_creb</i></sub> increasing from the standard value in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1010239#pcbi.1010239.t001" target="_blank">Table 1</a> to ~300% of the standard value, and <i>k</i><sub><i>basalp_CaMKII</i></sub> decreasing from the standard value in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1010239#pcbi.1010239.t001" target="_blank">Table 1</a> to 10% of the standard value.…”
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