Decreasing fluconazole susceptibility of clinical South African <i>Cryptococcus neoformans</i> isolates over a decade by Serisha D. Naicker (8648370)

The first regression of log of confirmed cases vs consecutive days for 4 of the total of 50 countries is shown. by Adam Kaplin (10156481)

Differences among the classes of CAMs. by Daniel P. Bradley (10306893)

“…A representative HPD <b>1466</b>, with a 50% effective concentration against HBV replication of 0.25 µM, decreased capsid and core protein accumulation by 50–90% in HepDES19 and HepG2.2.15 cells. …”

Crosslinking decreases the alignment of fibers associated with individual cells migrating out of spheroids. by Michael Pamonag (12295175)

Trial profile. by Chanel Avenant (409756)

“…The open-label WHICH clinical trial, conducted at two sites in South Africa from 2018–2019, randomized HIV-negative women aged 18–40 years to 150 mg DMPA-IM 12-weekly (n = 262) or 200 mg NET-EN 8-weekly (n = 259). We measured testosterone by UHPLC-MS/MS and SHBG by immunoassay in matched pairs of serum samples collected at baseline (D0) and at peak serum progestin levels at 25 weeks post initiation (25W) (n = 214–218 pairs). …”

Changes in lowland paddy soil fertility in the Philippines after 50 years of the Green Revolution by Atsushi Nakao (12396)

“…We found that the 2010s soils had a lower available N content, particularly in wetter regions, despite the high input of N fertilizers, whereas the available phosphorus (P) showed a six-fold increase from the 1960s to the 2010s. …”

SIINFEKL-specific CD8⁺ T cells treated with anti-CXCR3 decreased the polyfunctionality. by Camila Pontes Ferreira (6194006)

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…Compound <b>4f</b> exhibited potent EGFR inhibitory activity with an IC₅₀ value of 61 nM compared to that of Tamoxifen (IC₅₀ value of 69 nM), with EGFR inhibition of 83 and 84%, respectively, at a concentration of 10 μM. …”

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…Compound <b>4f</b> exhibited potent EGFR inhibitory activity with an IC₅₀ value of 61 nM compared to that of Tamoxifen (IC₅₀ value of 69 nM), with EGFR inhibition of 83 and 84%, respectively, at a concentration of 10 μM. …”

Image_2_Relative Diazotroph Abundance in Symbiotic Red Sea Corals Decreases With Water Depth.png by Arjen Tilstra (6915227)

“…We hypothesized that relative nifH gene copy numbers would decrease with water depth, assuming a related shift from autotrophy to heterotrophy. …”

Image_1_Relative Diazotroph Abundance in Symbiotic Red Sea Corals Decreases With Water Depth.tif by Arjen Tilstra (6915227)

“…We hypothesized that relative nifH gene copy numbers would decrease with water depth, assuming a related shift from autotrophy to heterotrophy. …”

Factors associated with abnormal left ventricular ejection fraction (decreased or increased) in patients with sepsis in the intensive care unit by Dong Geum Shin (6019568)

“…Patients were classified into three categories according to LV EF (group 1 –[EF<50%, n = 36], group 2 –[50≤EF<70%, n = 252], and group 3 –[EF≥70%, n = 78]). …”

Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability by Bárbara Arévalo (4053358)

“…The most active compound is 3-benzoylamino<i>-N</i>-(2-ethyl-phenyl)-benzamide or <b>F3</b>, blocking TASK-1 with an IC₅₀ of 148 nM, showing a reduced inhibition of TASK-3 channels and not a significant effect on different K⁺ channels. …”

Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability by Bárbara Arévalo (4053358)

“…The most active compound is 3-benzoylamino<i>-N</i>-(2-ethyl-phenyl)-benzamide or <b>F3</b>, blocking TASK-1 with an IC₅₀ of 148 nM, showing a reduced inhibition of TASK-3 channels and not a significant effect on different K⁺ channels. …”

Table1_Loss-of-function N178T variant of the human P2Y4 receptor is associated with decreased severity of coronary artery disease and improved glucose homeostasis.DOCX by Michael Horckmans (14206388)

“…In a population study comprising 50 patients with coronary artery disease (CAD) and 50 age-matched control individuals, we analyzed P2RY4 mutations and their potential association with CAD severity and fasting plasma parameters. …”

Table_1_Increased Neutrophil Count and Decreased Neutrophil CD15 Expression Correlate With TB Disease Severity and Treatment Response Irrespective of HIV Co-infection.DOCX by Lerato N. Ndlovu (9315464)

Repeated LSPC treatment prolongs survival of and decreases PrP^Res accumulation in a subset of prion-infected mice. by Heather Bender (363996)

DataSheet2_Loss-of-function N178T variant of the human P2Y4 receptor is associated with decreased severity of coronary artery disease and improved glucose homeostasis.ZIP by Michael Horckmans (14206388)

“…In a population study comprising 50 patients with coronary artery disease (CAD) and 50 age-matched control individuals, we analyzed P2RY4 mutations and their potential association with CAD severity and fasting plasma parameters. …”

DataSheet1_Loss-of-function N178T variant of the human P2Y4 receptor is associated with decreased severity of coronary artery disease and improved glucose homeostasis.ZIP by Michael Horckmans (14206388)

“…In a population study comprising 50 patients with coronary artery disease (CAD) and 50 age-matched control individuals, we analyzed P2RY4 mutations and their potential association with CAD severity and fasting plasma parameters. …”

DataSheet3_Loss-of-function N178T variant of the human P2Y4 receptor is associated with decreased severity of coronary artery disease and improved glucose homeostasis.ZIP by Michael Horckmans (14206388)

“…In a population study comprising 50 patients with coronary artery disease (CAD) and 50 age-matched control individuals, we analyzed P2RY4 mutations and their potential association with CAD severity and fasting plasma parameters. …”