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HRMECs treated with SUZ12 siRNA demonstrate increased miR-200b expression, decreased VEGF expression and decreased endothelial branching.
Published 2015“…<p><b>A,B:</b> Gene knockdown of EZH2 and SUZ12 was confirmed by qPCR. <b>C,D:</b> In HRMECs transfected with EZH2 siRNA in HG, miR-200b and VEGF were not significantly different from HG+control siRNA but decreased compared to NG+control siRNA. …”
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The rate of lariat formation is decreased two-fold by isoginkgetin treatment.
Published 2014“…The height of each bar indicates the fold change, from vehicle- to isoginkgetin-treated cells, in the mean fraction of reads aligning to each genic feature (<i>p</i><0.02 from two-tailed <i>t</i>-tests for all ratios). …”
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Loss of p115RhoGEF decreases junctional E-cadherin and promotes protrusions.
Published 2014“…<p>A) p115RhoGEF was knocked down in MCF7 cells and stained for E-cadherin and Actin. E-cadherin staining showed decreased junctional E-cadherin as compared to cells treated with control siRNA. …”
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