Opportunities, challenges and trade-offs with decreasing avoidable food waste in the UK حسب Patel, Shivalee

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Oxidative stress-induced Akt downregulation mediates green tea toxicity towards prostate cancer cells حسب Posadino, Anna Maria

"…Failure of PE to induce PC3 damage in cells overexpressing Akt further confirms its implication in the PE-elicited cell death. …"
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Credit bureaus and financial constraints do corruption matter? حسب Ben Ali, Mohamed Sami

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Greensporone C, a Freshwater Fungal Secondary Metabolite Induces Mitochondrial-Mediated Apoptotic Cell Death in Leukemic Cell Lines حسب Prabhu K.S.

"…Treatment with GC suppressed constitutively phosphorylated AKT and downregulated expression of inhibitor of apoptotic proteins XIAP, cIAP-1, and cIAP-2. …"
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Effects of superelastic nano-NiTi additions on electroless Ni –P coating properties under bending حسب MacLean M.

"…In this study, electroless Ni –P-nano-NiTi composite coatings containing 5.14 wt%, 6.07 wt%, and 7.02 wt % NiTi were subjected to three-point bend testing in order to determine bending properties. …"
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A robust experimental-based artificial neural network approach for photovoltaic maximum power point identification considering electrical, thermal and meteorological impact حسب Gowid, Samer

"…The results showed a decrease in the MSE of Vmp by 74.3% (from 1.6 V to 0.411 V), and in the MSE of Imp by 95% (from 4.4e−6 A to 2.16e−7 A), respectively. …"
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Salvia fruticosa Induces Vasorelaxation in Rat Isolated Thoracic Aorta: Role of the PI3K/Akt/eNOS/NO/cGMP Signaling Pathway حسب Anwar, M. Akhtar

"…Furthermore, SF induced Akt phosphorylation as well as increased cGMP levels in rings treated with increasing doses of SF. …"
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Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling حسب Chung, Jihyun

"…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …"
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Signaling pathways activated by PACAP in MCF-7 breast cancer cells حسب Zibara, Kazem

"…Moreover, selective inhibition of Src or PI3K resulted in a significant decrease in the phosphorylation of ERK and AKT, but not p38, demonstrating that PACAP signaling follows Src/Raf/ERK and PI3K/AKT pathways. …"
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Turning point in COVID-19 severity and fatality during the pandemic: a national cohort study in Qatar حسب Chemaitelly, Hiam

"…In the pre-omicron phase, first omicron wave, and combined phases, it was 2.01 (95% CI 1.90 to 2.13), 3.70 (95% CI 3.25 to 4.22) and 2.18 (95% CI 2.07 to 2.30) per 1000 person years, respectively. …"
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A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation... حسب Thirumal Kumar, D

"…An extensive two-step molecular dynamics (simple and complex) simulation (MDS) using GROMACS (GROningen MAchine for Chemical Simulations) was then initiated to analyze and understand the structural impact of the E17K mutation on the function of AKT1. The simple MDS analysis revealed that the E17K mutation decreases the compactness and intramolecular hydrogen bonds of the protein. …"
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Olive Leaves Extract and Oleuropein Improve Insulin Sensitivity in 3T3-L1 Cells and in High-Fat Diet-Treated Rats via PI3K/AkT Signaling Pathway حسب Hadrich, F.

"…Moreover, the cotreatment of EE 1/1000 or oleuropein with insulin increased considerably the expression of p-IRS, p85-pI3K, and p-AKT. In vivo model, the oral administration of oleuropein at 50 mg/kg in rats fed with high fat diet for 8 weeks reduced inflammation in liver and adipose tissues (WAT), improved glucose intolerance, and decreased hyperinsulinemia. …"
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Understanding the False Positive of Modified Martensitic Steels in Sweet & Sour Service Conditions Using a Point Defect Model Perspective حسب Martinez, Alan

"…These results indicate a critical point in temperature in the tests with only CO2, where resistance to pitting susceptibility is maximized due to a decrease in the cation vacancy diffusivity.…"
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Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects حسب Alsaad A.M.

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Prenatal alcohol exposure is associated with early motor, but not language development in a South African cohort حسب Hendricks, Gaironeesa

"…Objective:To investigate the association of prenatal alcohol exposure (PAE) and early neurodevelopment in the first 2 years of life, adjusting for maternal sociodemographic and psychosocial factors, in the Drakenstein Child Health Study (DCHS), a South African birth cohort study.Methods:The DCHS comprises a population-based birth cohort of 1143 children, of which, a subsample completed the Bayley Scales of Infant Development-III (BSID-III) at 6 (n = 260) and 24 months of age (n = 734). …"
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Coral reef resilience differs among islands within the Gulf of Mannar, southeast India, following successive coral bleaching events حسب Raj, K. Diraviya

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DEVELOPMENT AND EVALUATION OF VIRTUAL REALITY EXERGAMES FOR UPPER LIMB AMPUTEE REHABILITATION حسب MAZHAR, NOAMAN

"…User evaluation revealed positive user satisfaction(ratings: 3.8 to 4.5 on a 5-point Likert Scale). Quantitative analysis of the box and block test scores across 10 healthy participants for the motor skills assessment revealed a strong correlation (r = 0.99, P < 0.001) between training sessions and the evaluation scores. …"
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Enhancement of flocculation and dewaterability of a highly stable activated sludge using a hybrid system of organic coagulants and polyelectrolytes حسب Yousefi S.A.

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Impact of the fear of Covid-19 infection on intent to breastfeed; a cross sectional survey of a perinatal population in Qatar حسب Reagu, Shuja Mohd

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Appropriateness of gentamicin therapeutic drug monitoring at a Middle Eastern tertiary hospital setting: a retrospective evaluation and quality audit حسب Al-Sulaiti, Fatima Khalifa

"…Objective: This study aimed to evaluate the appropriateness of gentamicin therapeutic drug monitoring (TDM) at a tertiary care hospital in Qatar. Methods: A one-year quantitative retrospective chart review of all gentamicin TDM records was conducted. …"
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