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PBA decreases ER stress induced apoptosis.
Published 2010“…All three ER stress inducing agents elicited a two-three fold increase in pycnotic nuclei. The fraction of cells with pycnotic nuclei decreased with PBA treatment—in the thapsigargin treated cells, the number of pycnotic nuclei was identical to the untreated cells by 1 mM PBA, and by 5 mM PBA the fraction of cells with pycnotic nuclei reached basal levels in all three treatment groups (B).…”
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Isotonic Glycerol and Sodium Hyaluronate Containing Artificial Tear Decreases Conjunctivochalasis after One and Three Months: A Self-Controlled, Unmasked Study
Published 2015“…Conjunctivochalasis decreased from a mean LIPCOF degree of 2.9±0.4 on both eyes to 1.4±0.6 on the right (median decrease of -2 points, 95% CI from -2.0 to -1.0), and to 1.4±0.7 on the left eye (median decrease of -1 points, 95% CI from -2.0 to -1.0) (p<0.001 for both sides). …”
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HRMECs treated with SUZ12 siRNA demonstrate increased miR-200b expression, decreased VEGF expression and decreased endothelial branching.
Published 2015“…However, transfection of SUZ12 siRNA significantly reduced endothelial branching compared to HG+control siRNA. [NG+control siRNA = 5mM D-glucose + 100nM control siRNA, HG+control siRNA = 25mM D-glucose + 100nM control siRNA, HG+EZH2 siRNA = 25mM D-glucose + 100nM EZH2 siRNA, HG+SUZ12 siRNA = 25mM + 100nM SUZ12 siRNA; identical letters represent groups that are not significantly different; p < 0.05; n = 6; data expressed as mean ± SEM, normalized to U6 or β-actin and expressed as a fold change of NG+control siRNA].…”
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The combination of LPS and PFC caused faster clot initiation and decreased clot strength.
Published 2022“…Comparing groups, there is a significant decline in TEG MA in LPS-PFC3 group compared to LPS-SAL group at T72 and T96 time points (p<0.05). By RM ANOVA, the time effects were obscured by interaction with group: SAL-SAL, p = NS; LPS-SAL, MA increases with time; T0 v T72 and T96, p≤0.05; SAL-PFC: MA drops @ T96, p≤0.05; LPS-PFC: T0 v all others, p≤0.05 with a recovery at T96, (p≤0.05 compared to T72); SAL-PFC: no significant change, p = NS. …”
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SGK1 expression is significantly decreased in the prefrontal cortex of PTSD patients.
Published 2015“…Data are expressed as a mean fold change ± standard error of the mean (SEM) (<i>n</i> = 6), compared to healthy controls (<i>n</i> = 6). …”
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MiR-129-5p levels were decreased in mouse depression models.
Published 2025“…</b> Relative expression of miR-129-5p in the control and CRS groups. <b>M.</b> Relative expression of miR-129-5p in the CTX, HIP, and HB of control and CRS mice. …”
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Model performance according to number of variables by 5-fold cross-validation.
Published 2023Subjects: