Changes in neural activity were decreased in animals pre-exposed to 5-HT and <i>mod-1</i> mutants when the worms switched their locomotive direction. by Haruka Mori (8082215)

“…(F) Decreasing levels of RID neural activity during the transition periods from forward to backward locomotion in mock, 5-HT pre-exposed (p = 1.3 × 10⁻³), and <i>mod-1</i> mutant (p = 5.4 × 10⁻⁴) animals. …”

VAMP2 decreases 5-HT uptake and SERT cell surface expression in HEK-293 MSR cells by reducing the delivery rate of the transporter to the plasma membrane. by Heidi Kaastrup Müller (570207)

Subjects:

Knocking down of TRIM59 decreased the expression of cell cycle proteins. by Weihua Zhan (830500)

Decreased fibrin deposition in hypoxic C3−/− mice. by Eileen M. Bauer (337320)

Ifit2 deficiency results in decreased neuroinflammation upon RSA59 infection. by Jayasri Das Sarma (652473)

Effect of 5-HTR blockade on error pattern in the work/delay task. by Yukiko Hori (299784)

Subjects:

5-HT supplementation inhibits mitophagy. by Li Gao (131516)

Unilateral decrease of tracer-positive neurons after prion inoculation in the sciatic nerve. by Vladimir Ermolayev (260670)

WNT3 decreases GCP proliferation by inhibiting SHH dependent gene transcription. by Sandrine L. Anne (489755)

“…<p>(<i>A</i>) WNT3 decreased proliferation of GCPs by 40.3± 5.0% of the control (Con) (n=3) as measured by [³H]-Thymidine incorporation assay. …”

VPS34 inhibition decreases intracellular levels of cholesteryl-esters, blocks cholesterol uptake and enhances lysosomal degradation of LDLR. by Marek J. Kobylarz (9292599)

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(C)</b> Total cholesterol quantification (with fluorometric assay kit) in NIH3T3 cells depleted with sterols for 2 h or exposed to different CO₂ levels for 4 h (mean ± SE, <i>n</i> = 3 biological replicates per condition, **<i>P</i> < 0.01, nonsignificant (ns), two-sided Student’s <i>t</i> test). <b>(D, E)</b> The free cholesterol and cholesterol ester levels in the ER membrane from the cells as in <b>(C)</b>, were quantified with shotgun lipidomics analysis (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s007" target="_blank">S7 Fig</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s012" target="_blank">S5 Table</a>) (mean ± SE, <i>n</i> = 3 independent experiments, **<i>P</i> < 0.01, *<i>P</i> < 0.05, nonsignificant (ns) two-sided Student’s <i>t</i> test). …”

Drugs which cluster on the 'anxiolytic' group decrease 5-HT turnover in the brain. by Caio Maximino (100467)

“…<p>(A) Turnover rates, as measured by 5-HIAA:5-HT ratios, normalized to the values of vehicle-treated animals, for the following drugs: fluoxetine (FLX; chronic treatment with 10 mg/kg); chlordiazepoxide (CDZ; 0.02 mg/kg); clonazepam (CLZ; 0.05 mg/kg); diazepam (DZP; 1.25 mg/kg); buspirone (BUS; 50 mg/kg); ethanol (EtOH, 2.5%); dizocilpine (MK; 0.005 mg/kg); verapamil (VER; 5 mg/kg); WAY 100,635 (WAY; 0.03 mg/kg); and SB 224,289 (SB; 2.5 mg/kg). …”

Decreased responsivity to mechanical stimuli during DRN 5-HT neurons photostimulation. by Guillaume P. Dugué (620333)

Microparticles (MPs) from CD patients decrease 5-HT contraction in mouse aorta. by Daniela Leonetti (447114)

The coefficient of variation of the neural activity, unlike that of velocity, was decreased in animals pre-exposed to 5-HT and <i>mod-1</i> mutants. by Haruka Mori (8082215)

Activation of MAPKs in HCS-2/8 cells treated with 5-HT or agonist of each 5-HT₂ receptor and rescue effect of inhibitors of ERK1/2 and JNK on the BW723C86-decreased CCN2 production. by Ayaka Hori (4597795)

5-HT₇Dro knock-down decreases frequency of courtship behaviors. by Jaime Becnel (218896)

“…When compared with the parental lines 5-HT₇-Gal4 (Gal4) and UAS-sym-5-HT₇-dsRNA (UAS), the frequency of licking, curling and copulation attempts was significantly decreased. …”

The S178A mutation in Paxillin decreases adhesion size and axial ratio. by Mathew E. Berginski (214153)

5-HT supplementation induces mitochondrial damage. by Li Gao (131516)

The influence of 5-HT on MSQ43 cells. by Li Gao (131516)