Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients by Al-Amleh, Esraa K.

“…Platelet counts, on the other hand, dramatically decreased in both IM and (HU + IM). (4) Conclusion: Because the studied genes (BCL2, PP2A, CIP2A, and WT1) are participating in cell proliferation and death, the findings show that the examined genes are significant to understand the efficacy of various therapies. …”
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Oxidative stress-induced Akt downregulation mediates green tea toxicity towards prostate cancer cells by Posadino, Anna Maria

“…Failure of PE to induce PC3 damage in cells overexpressing Akt further confirms its implication in the PE-elicited cell death. …”
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Credit bureaus and financial constraints do corruption matter? by Ben Ali, Mohamed Sami

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Greensporone C, a Freshwater Fungal Secondary Metabolite Induces Mitochondrial-Mediated Apoptotic Cell Death in Leukemic Cell Lines by Prabhu K.S.

“…Treatment with GC suppressed constitutively phosphorylated AKT and downregulated expression of inhibitor of apoptotic proteins XIAP, cIAP-1, and cIAP-2. …”
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Salvia fruticosa Induces Vasorelaxation in Rat Isolated Thoracic Aorta: Role of the PI3K/Akt/eNOS/NO/cGMP Signaling Pathway by Anwar, M. Akhtar

“…Furthermore, SF induced Akt phosphorylation as well as increased cGMP levels in rings treated with increasing doses of SF. …”
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Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling by Chung, Jihyun

“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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Signaling pathways activated by PACAP in MCF-7 breast cancer cells by Zibara, Kazem

“…Moreover, selective inhibition of Src or PI3K resulted in a significant decrease in the phosphorylation of ERK and AKT, but not p38, demonstrating that PACAP signaling follows Src/Raf/ERK and PI3K/AKT pathways. …”
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A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation... by Thirumal Kumar, D

“…An extensive two-step molecular dynamics (simple and complex) simulation (MDS) using GROMACS (GROningen MAchine for Chemical Simulations) was then initiated to analyze and understand the structural impact of the E17K mutation on the function of AKT1. The simple MDS analysis revealed that the E17K mutation decreases the compactness and intramolecular hydrogen bonds of the protein. …”
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Olive Leaves Extract and Oleuropein Improve Insulin Sensitivity in 3T3-L1 Cells and in High-Fat Diet-Treated Rats via PI3K/AkT Signaling Pathway by Hadrich, F.

“…Moreover, the cotreatment of EE 1/1000 or oleuropein with insulin increased considerably the expression of p-IRS, p85-pI3K, and p-AKT. In vivo model, the oral administration of oleuropein at 50 mg/kg in rats fed with high fat diet for 8 weeks reduced inflammation in liver and adipose tissues (WAT), improved glucose intolerance, and decreased hyperinsulinemia. …”
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Modification of Pd/CeO2 catalyst by Atomic Layer Deposition of ZrO2 by Onn, Tzia Ming

“…Modification of a 1 wt% Pd/CeO2 catalyst by Atomic Layer Deposition of thin ZrO2 films was studied. …”
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Reactive Absorption of CO2 Using Ethylaminoethanol Promoted Aqueous Potassium Carbonate Solvent by Bhosale, Rahul Rambhau

“…In this paper, the kinetics of absorption of CO2 into an aqueous K2CO3 (20 wt %) promoted by ethylaminoethanol (EAE) solution (hereafter termed as APCE solvent) was studied in a glass stirred cell reactor using a fall in pressure method. …”
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Structural and mechanical characterization of stir cast Al–Al2O3–TiO2 hybrid metal matrix composites by Ahamad, N.

“…Aluminium matrix reinforced with aluminium oxide?titanium oxide (2.5, 5.0, 7.5 and 10 wt.%) in equal proportion were prepared by stir casting. …”
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Experimental investigation on the compressibility of Al/Al2O3 nanocomposites by Wagih, Ahmed

“…With up to 12 wt.% of Al2O3, microhardness increases from 62 to 150 HV due to the decrease of the crystallite size. …”
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Role of TiO2 and carbon nanotubes on polyethylene, and effect of accelerated weathering on photo oxidation and mechanical properties by Zagho M.M.

“…Addition of CNTs had negligible effect on the tensile strength but it kept the same approximate value of the original before the accelerated weathering (e.g., 23.2 MPa for 1 wt% of CNTs). CNTs also protected the samples even with the presence of TONPs because of the absorbance and antioxidants effects. …”
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Production and investigation of flexible nanofibers of sPEEK/PVP loaded with RuO2 nanoparticles by Chamakh, Mariem

“…Electrospinning technique was employed to fabricate composite nanofibers/nanoparticles of sulfonated polyether ether ketone, polyvinylpyrrolidone, and ruthenium oxide (sPEEK/PVP/RuO2). The samples were synthesized with different concentrations of hydrous ruthenium chloride of 2 wt%, 5 wt%, and 10 wt%, and then annealed at a temperature of 300 �C for 4 h to form the ruthenium oxide nanoparticles. …”
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Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects by Alsaad A.M.

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Biodegradable polysaccharide grafted polyacrylamide inhibitor for corrosion in CO2- saturated saline solution by Jalab, Rem

“…Electrochemical tests of Tafel and AC impedance, were used to determine the corrosion rate of carbon steel (C-steel) and protection efficiency in CO2-saturated 3.5 wt% NaCl solution. The surface morphology was characterized using FESEM coupled with EDX. …”
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Effect of concentration of DOC loaded TiO 2 nanotubes on the corrosion behavior of smart coatings by Ubaid F.

“…Various contents of the encapsulated TiO2 nanotubes (1, 3 and 5 wt%) were thoroughly dispersed into the epoxy matrix and the resulting composites were then applied on a cleaned steel substrate using doctor blade technique to develop smart coatings. …”
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Coral reef resilience differs among islands within the Gulf of Mannar, southeast India, following successive coral bleaching events by Raj, K. Diraviya

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Tailoring electrocatalytic properties of Pt nanoparticles grown on Ti3C2Tx MXene surface by Filip, Jaroslav

“…Composites containing 14 wt% Pt showed HER with an onset potential of −75.9 mV and a current density of −10 mA cm−2 achieved at −226 mV. …”
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