Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects by Alsaad A.M.

“…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …”
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Effect of hypoxia on metabolic markers and gene expression HIF-1 α in adipocytes by Younes, Noura B.

“…The exposure of adipocytes to 1% hypoxia significantly alters the transcript of hypoxia genes, and other genes involved in glucose (GLUT1, GLUT4) and lipid (PPAR-γ) metabolism, and is also linked to anaerobic metabolism with apoptosis and increased oxidative stress. …”
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Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2. by P, Sneha

“…Galactosemia type 2 is an autosomal recessive disorder characterized by the deficiency of galactokinase (GALK) enzyme due to missense mutations in GALK1 gene, which is associated with various manifestations such as hyper galactosemia and formation of cataracts. …”
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Opportunities, challenges and trade-offs with decreasing avoidable food waste in the UK by Patel, Shivalee

“…This study looks at the main stages of the food supply chain, and amasses the opportunities, challenges and trade-offs associated with surplus food redistribution to the UK economy. It highlights points in the food system where interventions can be made, to improve food’s circularity and sustainability potential. …”
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Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients by Al-Amleh, Esraa K.

“…Platelet counts, on the other hand, dramatically decreased in both IM and (HU + IM). (4) Conclusion: Because the studied genes (BCL2, PP2A, CIP2A, and WT1) are participating in cell proliferation and death, the findings show that the examined genes are significant to understand the efficacy of various therapies. …”
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MYD88, IRAK3 and Rheumatoid Arthritis pathogenesis: Analysis of differential gene expression in CD14 + monocytes and the inflammatory cytokine levels. by Gomes da Silva, Isaura Isabelle Fonseca

“…No significant differences were observed for MYD88 gene expression (FC = 1.20; p = 0.294) between patients and controls analyzed. …”
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Credit bureaus and financial constraints do corruption matter? by Ben Ali, Mohamed Sami

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Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanis... by Anwar-Mohamed, Anwar

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A robust experimental-based artificial neural network approach for photovoltaic maximum power point identification considering electrical, thermal and meteorological impact by Gowid, Samer

“…This paper aims to develop a robust and practical photovoltaic (PV) Maximum Power Point (MPP) identification tool developed using reliable experimental data sets. …”
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Novel potentials of the DPP-4 inhibitor sitagliptin against ischemia-reperfusion (I/R) injury in rat ex-vivo heart model by Al-Awar A.

“…Hearts were then isolated and subjected to two different I/R injury protocols: 10 min perfusion, 45 min regional ischemia, and 120 min reperfusion for infarct size (IS) measurement, or: 10 min perfusion, 45 min regional ischemia and 10 min reperfusion for biochemical analysis: nitric oxide synthases (NOSs) and DPP-4 activity, glucagon-like peptide-1 (GLP-1), Calcium, transient receptor potential vanilloid (TRPV)-1 and calcitonin gene-related peptide (CGRP) levels, transient receptor potential canonical (TRPC)-1 and e-NOS protein expression. …”
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PROFILE OF OXIDATIVE STRESS GENES IN RESPONSE TO OBESITY TREATMENT by AHMED, AMIRA

“…Aim: This study explores the impact of SNF on OS in diet induced obese (DIO) mice via profiling of OS genes and pathways in skeletal muscles related to the anti-obesity effect. …”
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A new family of boost active neutral point clamped inverter topology with reduced switch count by Siddique, Marif Daula

“…The neutral point is connected directly to the load terminals, which decreases the leakage current and makes it suitable for solar PV integration. …”
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Turning point in COVID-19 severity and fatality during the pandemic: a national cohort study in Qatar by Chemaitelly, Hiam

“…Conclusion The conclusion of the first omicron wave was a turning point in the severity of the pandemic. While vaccination and enhanced case management reduced severity gradually, the rapid accumulation of natural immunity during the first omicron wave appears to have played a critical role in driving this shift in severity.…”
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Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Ganji, Vijay

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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies by Fawaz E., Alanazi

“…Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …”
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies by Fawaz E., Alanazi

“…Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …”
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Understanding the False Positive of Modified Martensitic Steels in Sweet & Sour Service Conditions Using a Point Defect Model Perspective by Martinez, Alan

“…These results indicate a critical point in temperature in the tests with only CO2, where resistance to pitting susceptibility is maximized due to a decrease in the cation vacancy diffusivity.…”
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INTERACTION BETWEEN CLOCK GENE AND LIFESTYLE FACTOR IN RELATION TO OBESITY RISK FACTOR by ABDULKADER, HADIL

“…Women showed a strong association with obesity compared to men (OR: 1.51, 95% CL: 1.32-1.73), while smokers and ex-smokers had a decreased odds of having obesity by 21% and 12% respectively in comparison to nonsmokers. …”
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In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway by Kuttikrishnan, Shilpa

“…Moreover, NSP-B suppressed FOXM1-regulated genes, such as Aurora Kinases A and B, CDKs 4 and 6, and PLK1. …”
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Locations of Temporary Distribution Facilities for Emergency Response Planning by Pradhananga, Rojee

“…We assume that the individual demands in close vicinity are grouped at so-called aggregated demand points (ADPs). The distribution process initiates from a central supply point (CSP) which is a collection point that continuously acquires the resources and prepares them for distribution. …”
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