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_ akt » _ art (Expand Search)
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A systematic review on the impact of alcohol warning labels
Published 2023“…Findings on the effects of alcohol warning labels (AWLs) as a harm reduction tool have been mixed. This systematic review synthesized extant literature on the impact of AWLs on proxies of alcohol use. …”
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Oxidative stress-induced Akt downregulation mediates green tea toxicity towards prostate cancer cells
Published 2017“…Failure of PE to induce PC3 damage in cells overexpressing Akt further confirms its implication in the PE-elicited cell death. …”
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A Systematic Review of Antimicrobial Stewardship Interventions in the Emergency Department
Published 2017“…Methods: This study was completed as a systematic review. The following databases were searched from inception through November, 2016: MEDLINE, EMBASE, Cumulative Index to Nursing and Allied Health Literature, Scopus, and Web of Science. …”
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Greensporone C, a Freshwater Fungal Secondary Metabolite Induces Mitochondrial-Mediated Apoptotic Cell Death in Leukemic Cell Lines
Published 2018“…Treatment with GC suppressed constitutively phosphorylated AKT and downregulated expression of inhibitor of apoptotic proteins XIAP, cIAP-1, and cIAP-2. …”
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A systematic review of stability of medicines used in emergency medical service settings
Published 2020“…Medicines recommended to be refrigerated were not stable in a temperature-dependent manner. Although many medicines were stable, temperature-sensitive medicines degraded faster, while extreme cold produced various effects. …”
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Platelet Concentrate Treatments for Temporomandibular Disorders: A Systematic Review and Meta-analysis
Published 2021“…Objectives: This systematic review compared platelet concentrates (PCs) versus hyaluronic acid (HA) or saline/Ringer?…”
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Transforming the Capabilities of Artificial Intelligence in GCC Financial Sector: A Systematic Literature Review
Published 2022“…A systematic research is conducted to fill the gaps in the existing literature by picking the most relevant research papers (126) from the four most reputable online repositories based on the four research questions specified. …”
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Effect of Bariatric Surgery on Intima Media Thickness: A Systematic Review and Meta-Analysis
Published 2022“…Results: The meta-analysis of 30 trials, including 1488 subjects, demonstrated a significant decrease in IMT after bariatric surgery. …”
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Socket Shield Technique to Improve the Outcomes of Immediate Implant: A Systematic Review and Meta-Analysis
Published 2023“…Meta-analyses revealed that the immediate implants placed with SST had a statistically significant decrease in horizontal (MD = −0.28, 95% CI [−0.37, −0.19], p < 0.0001), vertical (MD = −0.85, 95% CI [−1.12, −0.58], p < 0.0001), and crestal (MD = −0.35, 95% CI [−0.56, −0.13], p = 0.002) bone loss, as well as probing depth (MD = −0.64, 95% CI [−0.99, −0.29], p = 0.0003). …”
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Non-steroidal anti-inflammatory drugs and bone healing in animal models-a systematic review and meta-analysis
Published 2021“…Methods: We performed a systematic review and meta-analysis of animal studies to estimate the effect of NSAID administration after bone fracture on healing outcomes. …”
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Salvia fruticosa Induces Vasorelaxation in Rat Isolated Thoracic Aorta: Role of the PI3K/Akt/eNOS/NO/cGMP Signaling Pathway
Published 2017“…Furthermore, SF induced Akt phosphorylation as well as increased cGMP levels in rings treated with increasing doses of SF. …”
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The Effects of Statin Therapy on Circulating Levels of Trimethylamine N-oxide: A Systematic Review and Meta-analysis
Published 2023“…This meta-analysis aimed to provide an answer as to whether statins do affect decreasing the plasma levels of atherogenic TMAO. Methods A systematic literature search in PubMed, Scopus, Embase, and Web of Science was performed from inception to January 1st, 2023. …”
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Cost-effectiveness research in cancer therapy: A systematic review of literature trends, methods and the influence of funding
Published 2017“…Design Systematic review. Setting A wide range of cancer-related research settings within healthcare, including health systems, hospitals and medical centres. …”
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Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling
Published 2019“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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Signaling pathways activated by PACAP in MCF-7 breast cancer cells
Published 2018“…Moreover, selective inhibition of Src or PI3K resulted in a significant decrease in the phosphorylation of ERK and AKT, but not p38, demonstrating that PACAP signaling follows Src/Raf/ERK and PI3K/AKT pathways. …”
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Orthodontic camouflage versus orthodontic-orthognathic surgical treatment in borderline class III malocclusion: a systematic review.
Published 2022“…Regarding the vertical jaw relation, one study reported a significant decrease in mandibular plane inclination in OC and a significant increase in OOS. …”
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Adaptive thermal comfort in the different buildings of Darjeeling Hills in eastern India – Effect of difference in elevation
Published 2018“…Whereas, the mean comfort temperature decreased with the elevation of the location and this difference was also statistically significant, t = −92.34 (df = 2607, p < 0.001). …”
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