Targeted point mutation (F639A) in the GluN1 subunit decreases ethanol sensitivity of NMDA receptors. by Carolina R. den Hartog (484817)

Adenosine inhibits AMPA EPSCs by decreasing presynaptic glutamate release. by Shouping Wang (402959)

mGluR5 receptor decreased glycinergic currents. by Zi-Yang Zhang (4988555)

“…(<b>F</b>) Postsynaptic loading of U-0126 or PD98059 prevented CHPG from decreasing glycinergic responses (U-0126, 107.6 ± 10.4% of baseline at 15–20 min post-CHPG, <i>t</i>[8] = 0.997, <i>p</i> = 0.348; PD98059, 93.1 ± 5.0% of baseline at 15–20 min post-CHPG, <i>t</i>[5] = 0.883, <i>p</i> = 0.418). …”

Variable importance plot (mean decrease accuracy and mean decrease Gini). by Fernando Martinez-Taboada (8655132)

Behavior of split^<50cM <i>ClvR</i> V1 with linkage. by Georg Oberhofer (3401438)

Behavior of split^<50cM <i>ClvR</i> V2 with linkage. by Georg Oberhofer (3401438)

“…<p>Incorporating linkage into split <i>ClvR</i> (split^<50cM <i>ClvR</i> V2) results in a graded increase in drive strength, and duration of <i>Rescue</i>/Cargo/gRNAs at high frequency, as the degree of linkage increases (map distance decreases). …”

Loss of C9orf72 decreases mTOR activation. by Janet Ugolino (3359054)

“…Knockdown of C9orf72 significantly decreased p-S6K1 levels compared with cells treated with control shRNA (n = 3, *<i>p</i><0.5). …”

Population dynamics modeling of split^50cM <i>ClvR</i> V1 introduced at a 50% release, with fitness cost per allele varying from 0–15%. by Georg Oberhofer (3401438)

Population dynamics of <i>Killer-Rescue</i>/Cargo, <i>ClvR</i> and split^50cM <i>ClvR</i> V2. by Georg Oberhofer (3401438)

PowerPoint Slides for: Patiromer Decreases Serum Potassium and Phosphate Levels in Patients on Hemodialysis by Bushinsky D.A. (3246690)

“…This was reduced to 38.1% (p = 0.009), 11.9% (p < 0.001), and 2.4% (p = 0.2) on patiromer. …”

SDG decreases iron-induced apoptosis in H9c2 cells. by Stephanie Puukila (568109)

Population behavior of split drive components <i>Rescue</i>^<i>tko</i> and Cas9/<i>Cleaver</i> alone and together as a complete split^50cM <i>ClvR</i> V2 elemen... by Georg Oberhofer (3401438)

Population dynamics modeling of split^50cM <i>ClvR</i> V1 drive introduced at different release percentages, and an example illustrating the role that LOF alleles play in... by Georg Oberhofer (3401438)

“…(<b>G-I)</b> One way to appreciate the power of the latent drive force provided by LOF alleles that segregate independently of the <i>Rescue</i>/Cargo is to consider a split^50cM <i>ClvR</i> population in which a <i>Rescue</i>/Cargo/gRNAs with no fitness cost has spread to allele fixation, the Cas9 driver chromosome has been completely eliminated (as would happen during drive if the presence of Cas9 resulted in a fitness cost to carriers, discussed below), and all endogenous copies of the essential gene have been rendered LOF (generation 0 in <b>G-I</b>). …”

SDG decreases iron-induced oxidative stress in H9c2 cells. by Stephanie Puukila (568109)

AGE-modification of laminin leads to a decrease in Kir4.1 function. by Kayla Thompson (4885036)

Drive dynamics for split^<50cM <i>ClvR</i>s with different genetic linkage and migration rates. by Georg Oberhofer (3401438)

Pretreatment with SDG prevents iron induced decrease in H9c2 cell size. by Stephanie Puukila (568109)

SDG decreases iron-induced MMP gene expression in H9c2 cells. by Stephanie Puukila (568109)

ChAT knock-down using an antisense oligodeoxynucleotide (AS-ODN) against ChAT, and decreased expression of ChAT in the DRG and spinal cord by Misaki Matsumoto (52354)

Beta-catenin signaling is decreased in intermediate progenitor cells. by Christopher A. Mutch (243132)

“…Arrows highlight examples of Tbr2+ cells outside the VZ, while arrowhead point to Tbr2+ cells still in the VZ. Tbr2+ cells have decreased d2EGFP signal in both the VZ and SVZ. …”