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5 w » 5 wt (Expand Search)
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), nn decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
w decrease » we decrease (Expand Search), _ decrease (Expand Search), _ decreased (Expand Search)
5 w » 5 wt (Expand Search)
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Brain and liver GCase activity are significantly decreased in heterozygous <i>GBA1</i> D409V KI mice, with varying differences in glucosphingolipid lipids in brain and liver.
Published 2021“…(A-B) GCase levels as assessed by the CBE/4-MU method are significantly decreased in the het <i>GBA1</i> D409V KI mice at 5 months of age in both brain (A) and liver (B). …”
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GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age.
Published 2021“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”
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MMR mutants show decreased mating-type silencing.
Published 2020“…The plasmids (<i>pRS425</i> and <i>pRS425-Gal10-MSH2</i>) were transformed to <i>msh2</i>Δ mutants in both WT (<i>his3Δ</i>) and UCC3505 backgrounds. Cells were five-fold serially diluted and then spotted onto SD-ura-leu + 2% glucose (left) or SD-ura-leu + 2% galactose (right) agar plates. …”