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621
Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer
منشور في 2025"…Following <i>LDHC</i> knockdown, we observed an increase in the secretion of tumor-derived pro-inflammatory cytokines (IFN-γ, GM-CSF, MCP-1, CXCL1), a decrease in the soluble levels of tumor-derived immunosuppressive factors (IL-6, Gal-9) and reduced tumor cell surface PD-L1 expression. …"
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622
Resilience-uncertainty nexus in building energy management integrated with solar system and battery storage
منشور في 2020"…The energy planning excluding uncertainty and events may be economically efficient but it is not resilient and practical. This paper provides a platform for energy management in the building under a set of realistic failures and uncertainties. …"
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623
Custom foot orthoses improve performance, but do not modify the biomechanical manifestation of fatigue, during repeated treadmill sprints
منشور في 2022"…</p><h3>Results</h3><p dir="ltr">Distance ran in 5 s decreased from first to last sprint (<i>P</i> < 0.001), yet with higher sprints 1–8 values for both EVA (<i>P</i> = 0.004) and TPU (<i>P</i> = 0.018) versus CON. …"
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624
Novel paclitaxel formulations solubilized by parenteral nutrition nanoemulsions for application against glioma cell lines
منشور في 2016"…The aim of this study is to investigate using nanoemulsion formulations as drug-delivery vehicles of paclitaxel (PX), a poor water-soluble anticancer drug. Two commercially available nanoemulsion fat formulations (Clinoleic 20% and Intralipid 20%) were loaded with PX and characterised based on their size, zeta potential, pH and loading efficiency. …"
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625
Solar syngas production via methanothermal reduction of strontium oxide
منشور في 2020"…<p dir="ltr">A solar methanothermal reduction of strontium oxide for the co-production of Sr and syngas is thermodynamically explored. …"
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626
Celsr3 is required for Purkinje cell maturation and regulates cerebellar postsynaptic plasticity
منشور في 2021"…In conclusion, Celsr3 is required for PCs maturation and regulates postsynaptic LTP and LTD through Wnt5a/cAMP and mGluR1/PKCα signaling respectively.…"
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627
Trends in prescribing and outcomes in obese versus non-obese patients receiving rivaroxaban therapy: an observational study using real-world data
منشور في 2023"…Within BMI categories, a similar increasing trend was observed in underweight, normal, and overweight patients, while from 2018 to 2020, there was a decreasing trend in rivaroxaban prescribing in all obese classes. …"
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628
The ortholog of human ssDNA-binding protein SSBP3 influences neurodevelopment and autism-like behaviors in <i>Drosophila melanogaster</i>
منشور في 2023"…Moreover, Ssdp overexpression led to differential changes in synaptic density in specific brain regions. We observed decreased levels of armadillo in the heads of Ssdp overexpressing flies, as well as a decrease in armadillo and wingless expression in the larval wing discs, implicating the involvement of the canonical Wnt signaling pathway in Ssdp functionality. …"
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629
Effect of Surface Treatment of Halloysite Nanotubes (HNTs) on the Kinetics of Epoxy Resin Cure with Amines
منشور في 2020"…Nonisothermal differential scanning calorimetry (DSC) analyses were performed on epoxy nanocomposites containing 0.1 wt.% of P-HNT, A-HNT, and F-HNT. Quantitative analysis of the cure kinetics of epoxy/amine system made by isoconversional Kissinger–Akahira–Sunose (<i>KAS</i>) and <i>Friedman</i> methods made possible calculation of the activation energy (<i>E</i><sub>α</sub>) as a function of conversion (α). …"
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630
Anabolic steroids-induced delirium
منشور في 2020"…Laboratory results showed a decreased plasma testosterone level of 9.59 nmol/l (10.4–37.4 nmol/l). …"
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631
Comparative study of the parameters affecting the performance of microchannels' heat exchangers: Latest advances review
منشور في 2023"…When the fluid is added with nanoparticles, like, Al2O3 and copper oxide (CuO) with different volumetric fractions (φ) of 0%, 0.5%, 1%, 1.5%, and 2%, the performance of the microchannel rises with rising the Reynolds number but conversely when the fluid is used in pure form the performance decreases with the rising value of Reynolds number. …"
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632
Dynamic stretching alone can impair slower velocity isokinetic performance of young male handball players for at least 24 hours
منشور في 2019"…Eight young male, elite handball players (age: 16.1±5.1 years) were tested prior to-, 3-minutes and 24-hours following the three conditions (DS, SS, Control) in a randomized and counterbalanced order. …"
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633
Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas
منشور في 2020"…We find that monthly shrinkage rates have a pronounced structured variability around the channel network with the shrinkage rate systematically decreasing farther away from the channels. …"
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634
Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
منشور في 2024"…Upon differentiating iPSCs lacking RFX6 into pancreatic islets, a significant decrease in PDX1 expression at the PF stage was observed, although this did not affect PPs co-expressing PDX1 and NKX6.1. …"
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635
Applying value-based strategies to accelerate access to novel cancer medications: guidance from the Oncology Health Economics Expert Panel in Qatar (Q-OHEP)
منشور في 2023"…<h3>Background</h3><p dir="ltr">In line with global trends, cancer incidence and mortality may have decreased for specific types of cancer in Qatar. However, the cancer-related burden on patients, healthcare systems, and the economy is expected to expand; thus, cancer remains a significant public healthcare issue in Qatar. …"
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636
Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
منشور في 2025"…Incorporating magnesium into PLA for 3D printing significantly affected the composites' dimensional stability and formation quality. While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. …"
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637
Life cycle assessment and sustainability enhancement of closed-loop carbon dioxide enhanced oil recovery: Field-scale evaluation in Qatar’s Dukhan Reservoir
منشور في 2025"…Global warming potential (GWP100) decreased from 2.00 × 10¹⁰ kg CO₂-eq in Year 1 to 1.20 × 10⁹ kg CO₂-eq in Year 21, with a 16% reduction observed in Year 1 under the fuel gas recovery scenario. …"
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638
Old subjects with sepsis in the emergency department: trend analysis of case fatality rate
منشور في 2019"…Over time the incidental admission rate (no. of sepsis-related admissions per 100 total admissions) increased from 4.1% (2009–2010) to 5.4% (2015–2016); P < 0.001, accompanied by a reduced CFR (from 38.0 to 18.4%; P < 0.001). …"
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639
Epibenthic communities from offshore platforms in the Arabian Gulf are structured by platform age and depth
منشور في 2021"…A step further is now required to determine whether these platform foundations should be converted to reefs after their decommissioning (i.e., Rigs to Reefs approach).…"
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640
Simultaneous adsorption-photocatalytic degradation of tetracycline by CdS/TiO<sub>2</sub> nanosheets/ graphene nanocomposites : Experimental study and modeling
منشور في 2021"…The highest obtained percentage removal of tetracycline (TC) (as a pharmaceutical pollutant model) was 84% under 180 minutes of visible light irradiation in the presence of the CdS-TNs/rGO(5) sample. …"