Chronic colitis induces marked changes in protein expression in the adult heart and blood. حسب Yanbo Tang (11457519)

Cinacalcet administered early in the inactive phase markedly decrease parathyroid Ki-67 index. حسب Søren Egstrand (10906087)

الموضوعات:

The proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases in <i>APC</i>-mutant colon tissues from FAP patients. حسب Tao Zhang (43681)

"…Results show that, in normal crypts, the distribution and proportion of cells staining for ALDH1 and CGA are very similar. In contrast, in <i>APC</i>-mutant tissues from FAP patients, the proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases. …"

The parameters of gas exchange markedly decreased in maize <i>zmstomagen1/2</i> mutant compared with in wild type (WT). حسب Juan-Juan Xu (18590868)

Group-level narrow- and broad-band spectral changes after hemispherotomy reveal a marked EEG slowing of the isolated cortex, robust across patients. حسب Michele Angelo Colombo (22446342)

Expression of lipid biosynthetic genes is decreased with polyamine depletion. حسب Yazmin E. Cruz-Pulido (20285238)

Withdrawal of Type I JAKinibs increased STAT phosphorylation, a phenomenon present but markedly lower in Type II JAKinibs. حسب Ilya Gurevic (1326786)

De-repression of gene expression and responsive histone marks. حسب Dana Lau-Corona (8861900)

"…<p>(<b>A</b>) Number of sites that show a significant decrease (Down) or a significant increase (Up) in each histone mark in E1/E2-KO male and E1/E2-KO female liver compared to sex-matched control liver. …"

Narrow- and broad-band spectral changes after hemispherotomy in an awake representative patient, displaying marked electroencephalography (EEG) slowing of the isolated cortex. حسب Michele Angelo Colombo (22446342)

"…In the middle panel, the topographies of Slow Delta Power, indexing the power spectral density (PSD) of low-frequency activity (0.5–2 Hz, hereby estimated under average reference for display purposes), show a marked inter-hemispheric asymmetry post-surgery. <b>(C)</b> The EEG PSD, averaged by geometric mean across intrahemispheric bipolar derivations, reveal an increase of slow frequency activity (<2 Hz) and a broad-band steepening of the PSD over the disconnected hemisphere post-surgery, which is evidenced in the inset graph by the linear fit of the PSD under double logarithmic axes (power-law fit). …"

3D interactions between the ligand and the protein_DNA complex in the first (C1) and second (C2) clusters. حسب Ahmed A. Gaber (13302308)

الموضوعات:

Region-specific gain and loss of repressive marks in aged somatic tissues. حسب Cheng-Lin Li (3620321)

Events O, A and B for the three time delay quantities. حسب Thomas Ward (688068)

<i>RTTN</i>-mutated organoids exhibit decreased proliferation and increased cell death at early stages. حسب Justine Guguin (9088672)

Deletion of microglial NKCC1 markedly impacts on baseline cell morphology and alters transformation to reactive microglia. حسب Krisztina Tóth (12009827)

"…(<b>D, E)</b> NKCC1 protein expression in a large number of randomly sampled NKCC1 KO microglia cells is markedly reduced compared to WT cells. …"

<b>Effect of Marked Weight Loss on Adipose Tissue Biology in People with Obesity and Type 2 Diabetes</b> حسب Dmitri Samovski (305400)

"…</p><p dir="ltr"><b>Results: </b>Weight loss: <a href="" target="_blank">i) </a><a href="" target="_blank">decreased adipose tissue </a>expression of genes related to extracellular matrix remodeling; ii) decreased adipose tissue expression of SERPINE 1 which encodes plasminogen activator inhibitor-1 (PAI-1); iii) did not decrease adipose tissue immune cell content or expression of genes involved in inflammation; iv) decreased adipose tissue ceramide content; v) decreased plasma <a href="" target="_blank">PAI-1 </a>and leptin concentrations and increased plasma high-molecular weight (HMW) adiponectin; and vi) decreased plasma small extracellular vesicle (sEV) concentration and the sEV content of microRNAs proposed to inhibit insulin action, and completely reversed the inhibitory effect of plasma sEVs on insulin signaling in myotubes.…"

Calpain activation, Hsp70.1 cleavage, and cathepsin B leakage. حسب Piyakarn Boontem (11663090)

الموضوعات:

Pericentric heterochromatin structural integrity is disrupted in the absence of CFDP1 due to loss of core heterochromatin protein, HP1α and H3K9me3 marks. حسب Gokul Gopinathan (7930679)

ComBat normalization markedly increases cross-study prediction when the studies have batch effects when using LASSO classifiers. حسب Yilin Gao (4335571)

ComBat normalization markedly increases cross-study prediction when the studies have batch effects when using XGBoost classifiers. حسب Yilin Gao (4335571)

Nemp1 KO mice display increased splenic stress erythropoiesis. حسب Didier Hodzic (132944)