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large decrease » marked decrease (Expand Search), large increases (Expand Search), large degree (Expand Search)
arl values » all values (Expand Search), auc values (Expand Search), cr values (Expand Search)
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ai large » i large (Expand Search), via large (Expand Search), _ large (Expand Search)
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Evolution of the PSD of the STN and D2 populations for increasing values of Dopamine Depletion <i>D</i><sub><i>d</i></sub>.
Published 2023“…<p>PSD of both STN and D2 nuclei related to low <b>(A)</b>, intermediate <b>(B)</b> and high <b>(C)</b> levels of dopamine depletion (<i>D</i><sub><i>d</i></sub> = 0.9, 0.97 and 1.05 respectively): for low values of <i>D</i><sub><i>d</i></sub> the system is characterized by the only STN-loop resonance; the increase of <i>D</i><sub><i>d</i></sub> leads to higher degrees of interaction and to the emergence of a unique resonance at an intermediate frequency.…”
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Post-hoc immunofluorescence analysis of photolabeled cells <i>in vivo</i> show that chromatin reorganization is reflected by increased CI values.
Published 2021“…This phenotype suggests that nuclear chromatin can move entirely as a rigid body without changing its internal architecture. To test if increases in CI values describing a loss of the line structure are associated with a three-dimensional redistribution of the photolabeled chromatin throughout the nucleus, we performed <i>in vivo</i> photolabeling of neurons 18 and 1 hour before fixation, leading to two groups of cells that will, on average, have undergone more or less spontaneous reorganization of chromatin. …”