Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists by Brian S. Gerstenberger (1936534)

“…Evidence generated through the characterization of conformationally restricted analogues supports the conclusion that the large potency enhancement is the result of the methyl substituent biasing the cyclohexane ring ground state conformation to favor that of the bound ligand and thus decreasing the ligand strain energy.…”

Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists by Brian S. Gerstenberger (1936534)

“…Evidence generated through the characterization of conformationally restricted analogues supports the conclusion that the large potency enhancement is the result of the methyl substituent biasing the cyclohexane ring ground state conformation to favor that of the bound ligand and thus decreasing the ligand strain energy.…”

Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists by Brian S. Gerstenberger (1936534)

“…Evidence generated through the characterization of conformationally restricted analogues supports the conclusion that the large potency enhancement is the result of the methyl substituent biasing the cyclohexane ring ground state conformation to favor that of the bound ligand and thus decreasing the ligand strain energy.…”

Region and cell microscopy. by Shuk C. Tsoi (21192243)

Statins increased neuronal soma membrane complexity. by Shuk C. Tsoi (21192243)

Statins resulted in smaller neuronal soma size. by Shuk C. Tsoi (21192243)

Statins induced flatter neuronal somas. by Shuk C. Tsoi (21192243)

There was no effect of statins on numbers of new neurons. by Shuk C. Tsoi (21192243)

(a) Molds; (b) Samples; (c)(d) Test devices. by Chenhao Li (822769)

“…<div><p>To solve the disposal of large quantities of construction waste clay, this study proposes a new method for preparing controlled low strength materials (CLSM). …”

Table 1_Effect of decreased suspended sediment content on chlorophyll-a in Dongting Lake, China.docx by Le Zhang (88249)

“…The reduction in SSC may influence chlorophyll-a (Chl-a) concentrations in water, thereby further affecting the aquatic ecological environment. …”

All-Atom Simulations Reveal the Effect of Membrane Composition on the Signaling of the NKG2A/CD94/HLA‑E Immune Receptor Complex by Martin Ljubič (15680161)

“…Additionally, we found that a large concentration of negative charge at the surface of the POPA-based membrane greatly increased the number of contacts with lipid molecules and significantly decreased the exposure of intracellular NKG2A ITIM regions to water molecules, thus likely halting the signal transduction process. …”

Effect of SS-31 on mice lung tissue inflammation induced by BLM. by Quankuan Gu (20539301)

Pathological staining and the pathological score. by Quankuan Gu (20539301)

Effect of SS-31 on mouse body weight and inflammatory factors in serum. by Quankuan Gu (20539301)

Mitochondrial structural changes and oxidative stress. by Quankuan Gu (20539301)

Occupancy model results using habitat as a covariate that affects occupancy, detection probability, or both (pre-COVID conditions only). by Ishana Shukla (20189612)

A 1:2000 scale map of the 2.12 km² study area: The UC Santa Cruz campus. by Ishana Shukla (20189612)

Detailed Diagram of the SAMCell Pipeline, with stages (a) Ground truth distance map creation for training/fine-tuning (b) Fine-tuning of the Segment Anything Model, where we choose... by Alexandra Dunnum VandeLoo (22209218)

CT outcome of HPDL-MIAIHD technique with other methods. by Naif Almakayeel (16846021)

Subjects:

CT outcome of HPDL-MIAIHD technique with recent methods. by Naif Almakayeel (16846021)

Subjects: