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year increase » may increase (Expand Search), greater increase (Expand Search)
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Increasing TPP side chain length decreases melanoma cell viability and clonogenic survival.
Published 2020“…The error bars for all data presented in Fig 2 represent the mean ± SEM. Results demonstrate that TPP derivatives decrease melanoma cell viability and clonogenic survival; and there is a structure-activity relationship between TPP side chain length and decreased viability and clonogenic survival.…”
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Inclusion of TPP side chains result in decreased melanoma cell mitochondria membrane potential, oxygen consumption, and increased DHE oxidation.
Published 2020“…The error bars for all data presented in Fig 3 represent the mean ± SEM. Results demonstrate that TPP derivatives preferentially accumulate in mitochondria; decrease mitochondria membrane potential and ATP-linked oxygen consumption; and increase DHE oxidation. …”
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Variable importance plot (mean decrease accuracy and mean decrease Gini).
Published 2020“…The higher the value of mean decrease accuracy or mean decrease Gini score, the higher the importance of the variable in the model.…”
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