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algorithm python » algorithm within (Expand Search), algorithms within (Expand Search), algorithm both (Expand Search)
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A Python Package for the Localization of Protein Modifications in Mass Spectrometry Data
Published 2022Subjects: -
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Python implementation of the Trajectory Adaptive Multilevel Sampling algorithm for rare events and improvements
Published 2021“…<div>This directory contains Python 3 scripts implementing the Trajectory Adaptive Multilevel Sampling algorithm (TAMS), a variant of Adaptive Multilevel Splitting (AMS), for the study of rare events. …”
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Functional and Structural Characterization of Mechanosensitive Piezo1 Channel in Disease
Published 2025“…AF3 predictions closely matched known protein structures (r.m.s.d. < 0.5), and in-silico mutagenesis revealed that several variants caused cavity alterations, hydrogen bond or salt bridge disruptions, and buried-to-exposed transitions. However, most algorithms struggled to distinguish gain-of-function (GoF) from loss-of-function (LoF) variants, with GoF variants showing lower pathogenicity scores despite clinical relevance.…”