Data_Sheet_1_‘WildLift’: An Open-Source Tool to Guide Decisions for Wildlife Conservation.pdf by Mariana Nagy-Reis (9472589)

“…Structured decision-making approaches can help evaluate such complex problems by formalizing objectives and constraints into functions that quantify the benefits and costs associated with each action. …”

Supplementary file 1_Single-cell and bulk transcriptomic analyses reveal PANoptosis-associated immune dysregulation of fibroblasts in periodontitis.zip by Erli Wu (17785482)

“…By integrating bulk transcriptomic data with machine learning algorithms, we identified and validated key PANoptosis-related genes, highlighting their potential as novel therapeutic targets.…”

Table_1_NAD metabolism-related genes provide prognostic value and potential therapeutic insights for acute myeloid leukemia.xlsx by Yuncan Cao (17398912)

“…</p>Methods<p>We utilized our large-scale RNA-seq data on 655 patients with AML and the NAD metabolism-related genes to establish a prognostic NAD metabolism score based on the sparse regression analysis. The signature was validated across three independent datasets including a total of 1,215 AML patients. ssGSEA and ESTIMATE algorithms were employed to dissect the tumor immune microenvironment. …”

Image_4_NAD metabolism-related genes provide prognostic value and potential therapeutic insights for acute myeloid leukemia.tif by Yuncan Cao (17398912)

“…</p>Methods<p>We utilized our large-scale RNA-seq data on 655 patients with AML and the NAD metabolism-related genes to establish a prognostic NAD metabolism score based on the sparse regression analysis. The signature was validated across three independent datasets including a total of 1,215 AML patients. ssGSEA and ESTIMATE algorithms were employed to dissect the tumor immune microenvironment. …”

DataSheet_1_NAD metabolism-related genes provide prognostic value and potential therapeutic insights for acute myeloid leukemia.docx by Yuncan Cao (17398912)

“…</p>Methods<p>We utilized our large-scale RNA-seq data on 655 patients with AML and the NAD metabolism-related genes to establish a prognostic NAD metabolism score based on the sparse regression analysis. The signature was validated across three independent datasets including a total of 1,215 AML patients. ssGSEA and ESTIMATE algorithms were employed to dissect the tumor immune microenvironment. …”

Image_1_NAD metabolism-related genes provide prognostic value and potential therapeutic insights for acute myeloid leukemia.tif by Yuncan Cao (17398912)

“…</p>Methods<p>We utilized our large-scale RNA-seq data on 655 patients with AML and the NAD metabolism-related genes to establish a prognostic NAD metabolism score based on the sparse regression analysis. The signature was validated across three independent datasets including a total of 1,215 AML patients. ssGSEA and ESTIMATE algorithms were employed to dissect the tumor immune microenvironment. …”

Image_2_NAD metabolism-related genes provide prognostic value and potential therapeutic insights for acute myeloid leukemia.tif by Yuncan Cao (17398912)

“…</p>Methods<p>We utilized our large-scale RNA-seq data on 655 patients with AML and the NAD metabolism-related genes to establish a prognostic NAD metabolism score based on the sparse regression analysis. The signature was validated across three independent datasets including a total of 1,215 AML patients. ssGSEA and ESTIMATE algorithms were employed to dissect the tumor immune microenvironment. …”

Image_3_NAD metabolism-related genes provide prognostic value and potential therapeutic insights for acute myeloid leukemia.tif by Yuncan Cao (17398912)

“…</p>Methods<p>We utilized our large-scale RNA-seq data on 655 patients with AML and the NAD metabolism-related genes to establish a prognostic NAD metabolism score based on the sparse regression analysis. The signature was validated across three independent datasets including a total of 1,215 AML patients. ssGSEA and ESTIMATE algorithms were employed to dissect the tumor immune microenvironment. …”

Table 1_Explainable machine learning model for predicting the outcome of acute ischemic stroke after intravenous thrombolysis.docx by Fanhai Bu (22315168)

“…Introduction<p>Acute ischemic stroke (AIS) patients often experience poor functional outcomes post-intravenous thrombolysis (IVT). …”

Image 13_Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patie... by Ran Du (552530)

“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technology</p>Results<p>Thirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”

Table_1_Development and analysis of a comprehensive diagnostic model for aortic valve calcification using machine learning methods and artificial neural networks.docx by Tao Xiong (287683)

“…First, the R software was used to identify differentially expressed genes (DEGs) and perform functional enrichment analysis. Next, we combined bioinformatics techniques with machine learning methodologies such as random forest algorithms and support vector machines to screen for and identify diagnostic markers of AVC. …”

Image 1_Polyamine metabolism related gene index prediction of prognosis and immunotherapy response in breast cancer.jpeg by Ruoya Wang (842048)

“…Additionally, we analyzed the immune microenvironment and enriched pathways across different subtypes using multiple algorithms. Finally, the “oncoPredict” R package was used to assess potential drug sensitivities in high-risk and low-risk groups.…”

Table 3_Unveiling ammonia-induced cell death: a new frontier in clear cell renal cell carcinoma prognosis.xlsx by Peize Yu (21837977)

“…Differentially expressed AICD-related genes were identified through differential expression analysis, univariate Cox regression, and machine learning algorithms (LASSO, random forest, and CoxBoost). A prognostic risk model was developed via multivariate Cox regression. …”

Image 4_Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patien... by Ran Du (552530)

“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technology</p>Results<p>Thirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”

Image 3_Unveiling ammonia-induced cell death: a new frontier in clear cell renal cell carcinoma prognosis.tif by Peize Yu (21837977)

“…Differentially expressed AICD-related genes were identified through differential expression analysis, univariate Cox regression, and machine learning algorithms (LASSO, random forest, and CoxBoost). A prognostic risk model was developed via multivariate Cox regression. …”

Supplementary file 2_The role of α-hydroxybutyrate in modulating sepsis progression: identification of key targets and biomarkers through multi-database data mining, machine learni... by Qing Lu (28914)

“…Sepsis-related targets were obtained from the GEO dataset GSE26440, and the intersection of these datasets was analyzed to reveal common targets. Functional enrichment analysis, protein-protein interaction (PPI) network construction, and machine learning algorithms (L1-LASSO, RF, and SVM) were applied to identify biomarkers. …”

Table_2_Development and analysis of a comprehensive diagnostic model for aortic valve calcification using machine learning methods and artificial neural networks.docx by Tao Xiong (287683)

“…First, the R software was used to identify differentially expressed genes (DEGs) and perform functional enrichment analysis. Next, we combined bioinformatics techniques with machine learning methodologies such as random forest algorithms and support vector machines to screen for and identify diagnostic markers of AVC. …”

Image 5_Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patien... by Ran Du (552530)

“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technology</p>Results<p>Thirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”

Image 10_Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patie... by Ran Du (552530)

“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technology</p>Results<p>Thirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”

Image 8_Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patien... by Ran Du (552530)

“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technology</p>Results<p>Thirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”