Table_3_Machine learning-based identification of CYBB and FCAR as potential neutrophil extracellular trap-related treatment targets in sepsis.xls حسب GuoHua You (17140984)

"…</p>Results<p>Analysis of the obtained DEGs and WGCNA screened a total of 3396 genes in 3 modules, and intersection of the results of both analyses with 69 NETs-related genes, screened out seven genes (S100A12, SLC22A4, FCAR, CYBB, PADI4, DNASE1, MMP9) using machine learning algorithms. Of these, CYBB and FCAR were independent predictors of poor survival in patients with sepsis. …"

Table_2_Machine learning-based identification of CYBB and FCAR as potential neutrophil extracellular trap-related treatment targets in sepsis.xls حسب GuoHua You (17140984)

"…</p>Results<p>Analysis of the obtained DEGs and WGCNA screened a total of 3396 genes in 3 modules, and intersection of the results of both analyses with 69 NETs-related genes, screened out seven genes (S100A12, SLC22A4, FCAR, CYBB, PADI4, DNASE1, MMP9) using machine learning algorithms. Of these, CYBB and FCAR were independent predictors of poor survival in patients with sepsis. …"

Image4_Construction of a mitochondrial dysfunction related signature of diagnosed model to obstructive sleep apnea.TIF حسب Qian Liu (135614)

"…Additionally, consensus clustering algorithms were used to conduct an unsupervised cluster analysis. …"

Table2_A Novel M7G-Related MicroRNAs Risk Signature Predicts the Prognosis and Tumor Microenvironment of Kidney Renal Clear Cell Carcinoma.XLS حسب Peng Hong (2828327)

"…M7G modification is a novel functional regulator of miRNA, and the researches on m7G-related miRNAs in kidney renal clear cell carcinoma (KIRC) are still insufficient. …"

Table4_A Novel M7G-Related MicroRNAs Risk Signature Predicts the Prognosis and Tumor Microenvironment of Kidney Renal Clear Cell Carcinoma.XLS حسب Peng Hong (2828327)

"…M7G modification is a novel functional regulator of miRNA, and the researches on m7G-related miRNAs in kidney renal clear cell carcinoma (KIRC) are still insufficient. …"

Image3_Construction of a mitochondrial dysfunction related signature of diagnosed model to obstructive sleep apnea.TIF حسب Qian Liu (135614)

"…Additionally, consensus clustering algorithms were used to conduct an unsupervised cluster analysis. …"

Image2_Construction of a mitochondrial dysfunction related signature of diagnosed model to obstructive sleep apnea.TIF حسب Qian Liu (135614)

"…Additionally, consensus clustering algorithms were used to conduct an unsupervised cluster analysis. …"

Table6_A Novel M7G-Related MicroRNAs Risk Signature Predicts the Prognosis and Tumor Microenvironment of Kidney Renal Clear Cell Carcinoma.DOCX حسب Peng Hong (2828327)

"…M7G modification is a novel functional regulator of miRNA, and the researches on m7G-related miRNAs in kidney renal clear cell carcinoma (KIRC) are still insufficient. …"

Image5_Construction of a mitochondrial dysfunction related signature of diagnosed model to obstructive sleep apnea.TIF حسب Qian Liu (135614)

"…Additionally, consensus clustering algorithms were used to conduct an unsupervised cluster analysis. …"

Table5_A Novel M7G-Related MicroRNAs Risk Signature Predicts the Prognosis and Tumor Microenvironment of Kidney Renal Clear Cell Carcinoma.XLS حسب Peng Hong (2828327)

"…M7G modification is a novel functional regulator of miRNA, and the researches on m7G-related miRNAs in kidney renal clear cell carcinoma (KIRC) are still insufficient. …"

Table3_A Novel M7G-Related MicroRNAs Risk Signature Predicts the Prognosis and Tumor Microenvironment of Kidney Renal Clear Cell Carcinoma.XLS حسب Peng Hong (2828327)

"…M7G modification is a novel functional regulator of miRNA, and the researches on m7G-related miRNAs in kidney renal clear cell carcinoma (KIRC) are still insufficient. …"

DataSheet2_A genome-wide association study of plasma concentrations of warfarin enantiomers and metabolites in sub-Saharan black-African patients.XLSX حسب Innocent G. Asiimwe (12340573)

"…In exploratory work, we conducted the first warfarin pharmacokinetics-related GWAS in sub-Saharan Africans and identified novel SNPs that will require external replication and functional characterization before they can be considered for inclusion in warfarin dosing algorithms.…"

Image2_A Novel M7G-Related MicroRNAs Risk Signature Predicts the Prognosis and Tumor Microenvironment of Kidney Renal Clear Cell Carcinoma.JPEG حسب Peng Hong (2828327)

"…M7G modification is a novel functional regulator of miRNA, and the researches on m7G-related miRNAs in kidney renal clear cell carcinoma (KIRC) are still insufficient. …"

Image_3_Serum-derived extracellular vesicles from breast cancer patients contribute to differential regulation of T-cell-mediated immune-escape mechanisms in breast cancer subtypes... حسب Rosalind Graham (10979421)

"…In vitro experiments confirmed that circulating EVs within breast cancer subtypes have functionally differing immunomodulatory capabilities, with EVs from patients with the most aggressive breast cancer subtype (TNBCs) demonstrating the most immune-suppressive phenotype (decreased CD3+HLA-DR+ but increased CD3+PD-L1 T cells, increased CD4+CD127-CD25hi T regulatory cells with associated increase in IL10 cytokine production). …"

Image_2_Serum-derived extracellular vesicles from breast cancer patients contribute to differential regulation of T-cell-mediated immune-escape mechanisms in breast cancer subtypes... حسب Rosalind Graham (10979421)

"…In vitro experiments confirmed that circulating EVs within breast cancer subtypes have functionally differing immunomodulatory capabilities, with EVs from patients with the most aggressive breast cancer subtype (TNBCs) demonstrating the most immune-suppressive phenotype (decreased CD3+HLA-DR+ but increased CD3+PD-L1 T cells, increased CD4+CD127-CD25hi T regulatory cells with associated increase in IL10 cytokine production). …"

Image_2_Serum-derived extracellular vesicles from breast cancer patients contribute to differential regulation of T-cell-mediated immune-escape mechanisms in breast cancer subtypes... حسب Rosalind Graham (10979421)

"…In vitro experiments confirmed that circulating EVs within breast cancer subtypes have functionally differing immunomodulatory capabilities, with EVs from patients with the most aggressive breast cancer subtype (TNBCs) demonstrating the most immune-suppressive phenotype (decreased CD3+HLA-DR+ but increased CD3+PD-L1 T cells, increased CD4+CD127-CD25hi T regulatory cells with associated increase in IL10 cytokine production). …"

Image_3_Serum-derived extracellular vesicles from breast cancer patients contribute to differential regulation of T-cell-mediated immune-escape mechanisms in breast cancer subtypes... حسب Rosalind Graham (10979421)

"…In vitro experiments confirmed that circulating EVs within breast cancer subtypes have functionally differing immunomodulatory capabilities, with EVs from patients with the most aggressive breast cancer subtype (TNBCs) demonstrating the most immune-suppressive phenotype (decreased CD3+HLA-DR+ but increased CD3+PD-L1 T cells, increased CD4+CD127-CD25hi T regulatory cells with associated increase in IL10 cytokine production). …"

IUTF Dataset(Enhanced): Enabling Cross-Border Resource for Analysing the Impact of Rainfall on Urban Transportation Systems حسب Xuhui Lin (19505503)

"…</p><h2>Data Structure</h2><p dir="ltr">The dataset is organized into four primary components:</p><ol><li><b>Road Network Data</b>: Topological representations including spatial geometry, functional classification, and connectivity information</li><li><b>Traffic Sensor Data</b>: Sensor metadata, locations, and measurements at both 5-minute and hourly resolutions</li><li><b>Precipitation Data</b>: Hourly meteorological information with spatial grid cell metadata</li><li><b>Derived Analytical Matrices</b>: Pre-computed structures for advanced spatial-temporal modelling and network analyses</li></ol><h2>File Formats</h2><ul><li><b>Tabular Data</b>: Apache Parquet format for optimal compression and fast query performance</li><li><b>Numerical Matrices</b>: NumPy NPZ format for efficient scientific computing</li><li><b>Total Size</b>: Approximately 2 GB uncompressed</li></ul><h2>Applications</h2><p dir="ltr">The IUTF dataset enables diverse analytical applications including:</p><ul><li><b>Traffic Flow Prediction</b>: Developing weather-aware traffic forecasting models</li><li><b>Infrastructure Planning</b>: Identifying vulnerable network components and prioritizing investments</li><li><b>Resilience Assessment</b>: Quantifying system recovery curves, robustness metrics, and adaptive capacity</li><li><b>Climate Adaptation</b>: Supporting evidence-based transportation planning under changing precipitation patterns</li><li><b>Emergency Management</b>: Improving response strategies for weather-related traffic disruptions</li></ul><h2>Methodology</h2><p dir="ltr">The dataset creation involved three main stages:</p><ol><li><b>Data Collection</b>: Sourcing traffic data from UTD19, road networks from OpenStreetMap, and precipitation data from ERA5 reanalysis</li><li><b>Spatio-Temporal Harmonization</b>: Comprehensive integration using novel algorithms for spatial alignment and temporal synchronization</li><li><b>Quality Assurance</b>: Rigorous validation and technical verification across all cities and data components</li></ol><h2>Code Availability</h2><p dir="ltr">Processing code is available at: https://github.com/viviRG2024/IUTDF_processing</p>…"