Addition of sphingosine-1-phosphate to human oocyte culture medium decreases embryo fragmentation by Zreik, Tony

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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion by Khoury, Nathalie

“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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The contribution of autophagy in glioblastoma multiforme cells treated with human recombinant arginase I-induced arginine deprivation. (c2018) by El Jbeily, Elie

“…All this results in a poor survival rate in GBM patients, which doesn’t exceed 1 year. …”
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Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59 by Ramada R. Khaswaneh (22224544)

“…</p><h3>Conclusion</h3><p dir="ltr">The loss of Factor H and CD59 in hypoxic MSCs can initiate their lysis and apoptosis mediated by activating MAC complex. Preserving the level of Factor H and CD59 in MSCs has significant clinical implication to increase their retention rate in hypoxic conditions and prolong their survival.…”

Fractionation and phytochemical composition of an ethanolic extract of Ziziphus nummularia leaves: antioxidant and anticancerous properties in human triple negative breast cancer c... by Rola Abdallah (22484130)

“…Results showed that ZNE and its Fraction 6 (F6) reduced the viability of MDA-MB-231 cells. F6 decreased MDA-MB-231 viability more than crude ZNE or its other fractions. …”

Aqueous urtica dioica leaves extract inhibits proliferation of acute myeloid leukemia cells in vitro by Rizk, Sandra

“…With respect to the proteins studied, treatment with Urtica dioica extract significantly increased the expression of the pro-apoptotic protein Bax with concomitant decrease in the anti-apoptotic protein Bcl-2 expression. …”
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β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo by Daaboul, Hamid E.

“…Also, there was a significant decrease in p-Erk and p-Akt protein levels. The treatment of mice (IP and topical) with HC caused a significant decrease in papilloma yield, incidence and volume. …”
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Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer by Shebaby, Wassim N.

“…Treatment of HaCaT-ras A5 and HaCaT-ras II4 cells with F2 fraction resulted in the accumulation of cells in the sub-G1 apoptotic phase and decreased the population of cells in the S and G2/M phases. …”
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The antiproliferative and pro-apoptotic effect of kefir on human leukemic cell lines. (c2008) by Maalouf, Katia E.

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Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells by Al Sayyed, Fatima

“…Amplification of MYC-N proto-oncogene is highly associated with clinically aggressive disease, recurrence and treatment failure. The highly malignant rate in neuroblastoma is likely due to the continuous acquisition of genetic aberrations in undifferentiated neuroblastoma cancer stem cells (CSCs). …”
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Drug-free phototherapy of superficial tumors by Mehanna, Stephanie

“…After a 9-h exposure in vitro, the viability of Human Malignant Melanoma cells (A375) decreased by around 70%. Western blot analysis suggested an apoptotic cell death confirmed by the upregulation of Bax, cleaved PARP/caspase-3/8, cytochrome c, and t-bid. …”
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