Image1_Targeting HSP90 Inhibits Proliferation and Induces Apoptosis Through AKT1/ERK Pathway in Lung Cancer.TIF حسب Mengyuan Niu (3847543)

"…In both human and mouse lung cancer cell lines, knocking down HSP90AA1 promoted cell apoptosis through the inhibition of the pro-survival effect of AKT1 by decreasing the phosphorylation of itself and its downstream factors of mTOR and BAD, as well as downregulating Mcl1, Bcl-xl, and Survivin. …"

Table1_Targeting HSP90 Inhibits Proliferation and Induces Apoptosis Through AKT1/ERK Pathway in Lung Cancer.pdf حسب Mengyuan Niu (3847543)

"…In both human and mouse lung cancer cell lines, knocking down HSP90AA1 promoted cell apoptosis through the inhibition of the pro-survival effect of AKT1 by decreasing the phosphorylation of itself and its downstream factors of mTOR and BAD, as well as downregulating Mcl1, Bcl-xl, and Survivin. …"

Table_1_Targeting NAT10 Induces Apoptosis Associated With Enhancing Endoplasmic Reticulum Stress in Acute Myeloid Leukemia Cells.docx حسب Jie Zi (8203833)

"…NAT10 was found to be highly expressed in patients with AML, and increased NAT10 expression was associated with poor outcomes. Additionally, targeting NAT10 via the shRNA knockdown and its pharmacotherapeutic inhibitor resulted in inhibition of cell proliferation, induction of cell cycle arrest in the G1 phase, and apoptosis in AML cells. …"

IRE1 depletion induces cell cycle arrest independently of apoptosis. حسب Iratxe Zuazo-Gaztelu (21071939)

STAT6 siRNA sequences 1 and 4 induce apoptosis. حسب Carmen Salguero-Aranda (6690044)

Supplementary Material for: MicroRNA-296-5p Promotes Cell Invasion and Drug Resistance by Targeting Bcl2-Related Ovarian Killer, Leading to a Poor Prognosis in Pancreatic Cancer حسب Okazaki J. (7436723)

"…Moreover, these transfectants showed a significantly lower apoptosis rate in response to 5-fluorouracil and gemcitabine with a decrease of <i>BOK</i> expression, suggesting a role of miR-296-5p in drug resistance. …"

Allosteric Regulation of IGF2BP1 as a Novel Strategy for the Activation of Tumor Immune Microenvironment حسب Yang Liu (4829)

الموضوعات:

Allosteric Regulation of IGF2BP1 as a Novel Strategy for the Activation of Tumor Immune Microenvironment حسب Yang Liu (4829)

الموضوعات:

Allosteric Regulation of IGF2BP1 as a Novel Strategy for the Activation of Tumor Immune Microenvironment حسب Yang Liu (4829)

الموضوعات:

Allosteric Regulation of IGF2BP1 as a Novel Strategy for the Activation of Tumor Immune Microenvironment حسب Yang Liu (4829)

الموضوعات:

Allosteric Regulation of IGF2BP1 as a Novel Strategy for the Activation of Tumor Immune Microenvironment حسب Yang Liu (4829)

الموضوعات:

Decoding the Structure–Property–Function Relationships in Covalent Organic Frameworks for Sustainable Battery Design حسب Tarek M. Madkour (4921354)

الموضوعات:

Table_1_Bacterial Cyclodipeptides Target Signal Pathways Involved in Malignant Melanoma.docx حسب Mayra Xóchitl Durán-Maldonado (9162404)

The accumulation of autophagosomes is associated with the mechanism by which <i>Tp</i> induces apoptosis and inhibits its own clearance in HMC3 cells. حسب Yun-Ting Hu (16871924)

الموضوعات:

RAD54L overexpression promotes cell viability and inhibits the inflammatory response and apoptosis of IL-1β-induced human chondrocytes. حسب Zhengnan Li (356544)

الموضوعات:

Lymphomas infected with ΔEBNA2 EBV plus Myc have decreased NF-κB2 signaling and decreased STAT3 activity compared to lymphomas with ΔEBNA2 EBV alone. حسب Jillian A. Bristol (5566289)

Image 1_Kaixin San Jiawei granule improves cognitive function and alleviates neuronal damage in Alzheimer’s disease via multi-component and multi-target mechanisms.tif حسب Wei Liu (20030)

"…</p>Conclusion<p>KSG improves cognitive function and attenuates Aβ-induced neuronal damage in AD through multi-component, multi-target synergistic mechanisms. These effects appear to be mediated by modulation of the cholinergic system, inhibition of oxidative stress and inflammation, and suppression of neuronal apoptosis. …"

Image 2_Kaixin San Jiawei granule improves cognitive function and alleviates neuronal damage in Alzheimer’s disease via multi-component and multi-target mechanisms.tif حسب Wei Liu (20030)

"…</p>Conclusion<p>KSG improves cognitive function and attenuates Aβ-induced neuronal damage in AD through multi-component, multi-target synergistic mechanisms. These effects appear to be mediated by modulation of the cholinergic system, inhibition of oxidative stress and inflammation, and suppression of neuronal apoptosis. …"

Image_6_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF حسب Yang Kong (3376658)

Image_4_The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma.TIF حسب Yang Kong (3376658)