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values decrease » values increased (Expand Search), largest decrease (Expand Search)
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DSS-induced colitis mouse model.
Published 2019“…For most marker genes, DSS-treatment caused large increases/decreases in mRNA levels. Both CsA and EPHX2i treatment tended to restore expression levels back toward baseline (<i>Il1b</i>, <i>Ccr6</i>, <i>Sstr2</i>, <i>Lgr5</i>) or to near baseline levels (<i>Tnf</i>, <i>Ltb</i>, <i>Rela</i>). …”
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Image_1_Multi-Component Comparative Pharmacokinetics in Rats After Oral Administration of Fructus aurantii Extract, Naringin, Neohesperidin, and Naringin-Neohesperidin.pdf
Published 2020“…There were significant differences in pharmacokinetic parameters for naringenin and hesperetin between the compatibility, FA extract group vs monomer group: ① remarkable increases in the values of AUC<sub>(0–∞)</sub>, AUC<sub>(0–t)</sub> and C<sub>max</sub>; ② obvious decrease of CL<sub>Z/F</sub>; and ③ longer t<sub>max</sub> and t<sub>1/2z</sub>. …”
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Table_1_Multi-Component Comparative Pharmacokinetics in Rats After Oral Administration of Fructus aurantii Extract, Naringin, Neohesperidin, and Naringin-Neohesperidin.docx
Published 2020“…There were significant differences in pharmacokinetic parameters for naringenin and hesperetin between the compatibility, FA extract group vs monomer group: ① remarkable increases in the values of AUC<sub>(0–∞)</sub>, AUC<sub>(0–t)</sub> and C<sub>max</sub>; ② obvious decrease of CL<sub>Z/F</sub>; and ③ longer t<sub>max</sub> and t<sub>1/2z</sub>. …”
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Table_2_Multi-Component Comparative Pharmacokinetics in Rats After Oral Administration of Fructus aurantii Extract, Naringin, Neohesperidin, and Naringin-Neohesperidin.docx
Published 2020“…There were significant differences in pharmacokinetic parameters for naringenin and hesperetin between the compatibility, FA extract group vs monomer group: ① remarkable increases in the values of AUC<sub>(0–∞)</sub>, AUC<sub>(0–t)</sub> and C<sub>max</sub>; ② obvious decrease of CL<sub>Z/F</sub>; and ③ longer t<sub>max</sub> and t<sub>1/2z</sub>. …”