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Rfg1, a protein related to the hypoxic repressor Rox1 of Saccharomyces cerevisiae, is a novel DNA binding repressor of filamentation in the pathogenic yeast, Candida albicans
Published 2001“…The C. albicans clone also encoded an HMG protein which was capable of repression of an hypoxic gene in a S. cerevisiae rox1 deletion strain. Gel retardation experiments using the purified HMG-domain of this protein demonstrated that it was capable of binding specifically to a S. cerevisiae hypoxic operator DNA sequence. …”
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masterThesis -
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Evaluation of an Integrated PTSC/Thermal Energy Storage System Using Nano-Fluid Particles
Published 2016Get full text
doctoralThesis -
104
The Use of Transferrin and Ultrasound in Cancer Treatment
Published 2019Get full text
doctoralThesis -
105
Human recombinant arginase I (Co)-PEG5000 [HuArgI (Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human glioblastoma cells
Published 2015“…In this study, we attempt to target Arginine auxotrophy in glioblastoma multiforme (GBM) cells using a pegylated recombinant human Arginase I cobalt [HuArgI (Co)-PEG5000]. …”
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Tuberculosis following programmed cell death receptor-1 (PD-1) inhibitor in a patient with non-small cell lung cancer. Case report and literature review
Published 2022“…Nonetheless, tuberculosis (TB) reactivation during their use is increasingly recognized and reported. Herein, we present a 58-year-old lady with advanced non-small cell lung cancer (NSCLC) ALK-negative, EGFR wild, and PD-L1 immune histochemistry (IHC) strongly positive in 95% of tumor cells, on ongoing treatment with Pembrolizumab as a first-line monotherapy. …”
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Use of local discarded materials in concrete
Published 2014“…This paper presents the results obtained on the use of steel slag, gravel and gabbro in concrete. …”
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Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis
Published 2019“…<h3>Background</h3><p dir="ltr">Brief intervention is a critical method for identifying patients with problematic substance use in primary care settings and for motivating them to consider treatment options. …”
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One Dimensional Seismic Site Response Analysis of United Arab Emirates
Published 2021Get full text
doctoralThesis -
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Identification of potential transcription factors that enhance human iPSC generation
Published 2020“…In addition, reprogramming efficacy has been evidenced to be affected by disease mutations that are present in patient samples. In this study, using RNA-seq platform we have identified and validated the differential gene expression of five transcription factors (TFs) (GBX2, NANOGP8, SP8, PEG3, and ZIC1) that were associated with a remarkable increase in the number of iPSC colonies generated from a patient with Parkinson's disease. …”
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Defining digital addiction: Key features from the literature
Published 2020“…<p dir="ltr">Within recent years there has been increasing societal concern around the compulsive and excessive use of digital and Internet-enabled devices, such as the use of social media or online video gaming, and associated psychological and physical harms. …”
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PDX1<sup>−</sup>/NKX6.1<sup>+</sup> progenitors derived from human pluripotent stem cells as a novel source of insulin‐secreting cells
Published 2020“…</p><h3>Materials and Methods</h3><p dir="ltr">Three different hPSC lines were differentiated into PDX1<sup>−</sup>/NKX6.1<sup>+</sup> progenitors, which were further differentiated into insulin-secreting cells using two different protocols. …”
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Comparative efficacy and safety of PD-1/PD-L1 inhibitors in triple negative breast cancer: a systematic review and network meta-analysis of randomized controlled trials
Published 2023“…They were associated with an increase in immune-related adverse effects. When used early in the course of TNBC, PD-1/PD-L1 inhibitors exert their maximum benefit. …”
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Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF) 1
Published 2015“…In this study, we attempt to target both the urokinase plasminogen activator and the mitogen-activated protein kinase pathway in acute myeloid leukemia (AML) cell lines and primary AML blasts using PrAgU2/LF, a urokinase-activated anthrax lethal toxin. …”
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<i>Asterarcys quadricellulare</i> (Chlorophyceae) protects H9c2 cardiomyoblasts from H<sub>2</sub>O<sub>2</sub>-induced oxidative stress
Published 2022“…The outcome of our study highlighted the possible use of the local <i>A. quadricellulare</i> strain QUCCCM10 as a natural, safe, and efficient antioxidant to prevent cardiovascular diseases.…”
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