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values decrease » values increased (Expand Search), largest decrease (Expand Search)
use increased » cases increased (Expand Search), also increased (Expand Search), rate increased (Expand Search)
c large » _ large (Expand Search), i large (Expand Search), b large (Expand Search)
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Supplementary Materials for Genotypic and phenotypic spectrum and pathogenesis of WNT1 variants in a large cohort of patients with OI / osteoporosis
Published 2022“…We reported for the first time a decreased β-catenin level in the bone of patient 10 with c.677C>T and c.502G>A compared to the healthy control, which revealed the potential mechanisms of WNT1-induced skeletal phenotypes. …”
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Longer polyQ sequences decrease the nuclear localization of AR in the absence of hormone.
Published 2022Subjects: -
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