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Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s disease
Published 2017“…ROC analysis showed a sensitivity of 85% and a specificity of 84% (AUC = 0.88) in distinguishing AD from controls. …”
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Diagnosing type 2 diabetes using Hemoglobin A1c: a systematic review and meta-analysis of the diagnostic cutpoint based on microvascular complications
Published 2020“…</p><h3>Conclusions</h3><p dir="ltr">The prevalence of nephropathy and moderate retinopathy was increased in subjects with HbA1c values ≥ 6.5% confirming the high specificity of this value for diagnosing T2DM; however, at HbA1c < 6.5% retinopathy increased at age > 55 years and, most strikingly, in African-Americans, suggesting there may be excess microvascular complication prevalence (particularly nephropathy) in individuals below the diabetes diagnostic threshold.…”
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The balancer model in international relations. (c2009)
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Implementation of trust region methods in optimization. (c1998)
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Regulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes
Published 2011“…MRP4-deficient mice displayed enhanced cardiac myocyte cAMP formation, contractility, and cardiac hypertrophy at 9 mo of age, an effect that was compensated transiently by increased phosphodiesterase expression at young age. …”
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Multisystem inflammatory syndrome in children (MIS-C) secondary to COVID-19 mRNA vaccination – A case report from Qatar
Published 2022“…After he received appropriate immunomodulatory treatment (IVIG and methylprednisolone) as per the guideline, he showed marked clinical improvement. Our case report highlights the need to consider MIS-C as a potential differential in young patients who present with unexplained multisystem illness with increased inflammatory markers and negative microbiologic work-up. …”
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Selective changes in cytosolic β-adrenergic cAMP signals and L-type Calcium Channel regulation by Phosphodiesterases during cardiac hypertrophy
Published 2020“…In SHAM and CH LVMs, a short isoprenaline stimulation (Iso, 100 nM, 15 s) elicited a similar transient increase in cAMP with a half decay time (t1/2off) of ~50 s. …”
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Tuning dual-Fe sites in Fe–N–C dual-atom catalysts by sulfur doping for enhanced CO₂ electroreduction: Insights from the first-principles computations
Published 2025“…<p dir="ltr">This study explores the impact of sulfur doping on the surface and electronic structure of Fe–N–C dual-atom catalysts for electrochemical CO<sub>2</sub> reduction, using first-principles density functional theory (DFT) computations. …”
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Reduced HDL-cholesterol in long COVID-19: A key metabolic risk factor tied to disease severity
Published 2024“…Findings indicated significant metabolic shifts in severe Long-COVID-19 cases, mainly a marked drop in HDL-C levels and a doubled increase in ferritin levels and insulin resistance compared to the mild cases and controls. …”
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Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases
Published 2010“…When performed within 4 weeks of chemotherapy, PET had a negative predictive value of 13.3% and a positive predictive value of 94.3%. …”
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Land surface temperature responses to land use dynamics in urban areas of Doha, Qatar
Published 2024“…Specifically, the mean summer LST increases by 7.64 °C (0.34 °C annually), and the mean winter LST decreases by 4.87 °C (0.22 °C annually). …”
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Exploring serum glycome patterns after moderate to severe traumatic brain injury: A prospective pilot study
Published 2022“…Two brain-specific structures, HexNAc5Hex3DeoxyHex0NeuAc0 and HexNAc5Hex4DeoxyHex0NeuAc1, were substantially increased early after injury in patients with unfavorable outcome (GOS-E≤4) (area under the curve [AUC]=0·75 [95%CI 0·59-0·90] and AUC=0·71 [0·52-0·89], respectively). …”
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Land surface temperature responses to land use dynamics in urban areas of Doha, Qatar
Published 2024“…Specifically, the mean summer LST increases by 7.64 °C (0.34 °C annually), and the mean winter LST decreases by 4.87 °C (0.22 °C annually). …”
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Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59
Published 2024“…This has been associated with upregulation of MAC complex and increased level of cell lysis and apoptosis marked by downregulation of PI3K and upregulation of Annexin v and Caspase-3.…”