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HSF2 reduced the decrease in the MMP in Caco-2 cells, which were observed by laser confocal microscopy.
Published 2025“…Red fluorescence indicated that there was no obvious abnormality in the MMP, while green fluorescence represented a decrease in the MMP. B: Statistical bar chart of the ratio of red to green fluorescence, <i>P</i> value of less than 0.05 was identified as* and <i>P</i> value of less than 0.01 was identified as**. …”
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MEDOC: A Fast, Scalable, and Mathematically Exact Algorithm for the Site-Specific Prediction of the Protonation Degree in Large Disordered Proteins
Published 2025“…To address this problem, we developed "multisite extent of deprotonation originating from context" (MEDOC) to determine the degree of protonation of a protein based on the local sequence context of each ionizable residue. …”
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B2 decreases glycolytic intermediates in cells.
Published 2025“…The box indicates the clustering of decreased downstream glycolytic intermediates in B2-treated cells. …”
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Laser Induced Shockwave to Study Cell Injury
Published 2025“…Shockwaves were used to simulate mechanical stress and induce cell death, with a focus on the role of lysosomal enzyme Cathepsin B. Acridine orange staining revealed that cells closest to the shockwave epicenter experienced the greatest decrease in lysosomal intensity, indicating degradation.…”
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