Chronic colitis induces marked changes in protein expression in the adult heart and blood. حسب Yanbo Tang (11457519)

Cinacalcet administered early in the inactive phase markedly decrease parathyroid Ki-67 index. حسب Søren Egstrand (10906087)

General procedure for the synthesis of the target compounds 11a,b,15a,b. حسب Ahmed A. Gaber (13302308)

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General procedures for the synthesis of the key compounds 7a, b, 9, and 10. حسب Ahmed A. Gaber (13302308)

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Binding of compound 12b with DNA-Topo II complex. حسب Ahmed A. Gaber (13302308)

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Binding of compound 11a with DNA-Topo II complex. حسب Ahmed A. Gaber (13302308)

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The proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases in <i>APC</i>-mutant colon tissues from FAP patients. حسب Tao Zhang (43681)

"…In contrast, in <i>APC</i>-mutant tissues from FAP patients, the proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases. Crypt cell levels are indicated that range from crypt bottom (level 1) to crypt top (level ~82). …"

The contributions of amino acids around 10 Å of the ligand to the binding free energy. حسب Ahmed A. Gaber (13302308)

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3D interactions between the ligand and the protein_DNA complex in the first (C1) and second (C2) clusters. حسب Ahmed A. Gaber (13302308)

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Binding of compound 16 with DNA-Topo II complex. حسب Ahmed A. Gaber (13302308)

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Binding of amsacrine with DNA-Topo II complex. حسب Ahmed A. Gaber (13302308)

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The center of mass distances between the protein-DNA complex and the ligand (Blue line), and the protein and DNA (red line). حسب Ahmed A. Gaber (13302308)

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Fig 12 - حسب Ahmed A. Gaber (13302308)

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Effect of compound 16 on stages of the cell death process in HCT-116 cells after 48 h treatment. حسب Ahmed A. Gaber (13302308)

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General procedure for the synthesis of the target compounds 16–20. حسب Ahmed A. Gaber (13302308)

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The number of clusters, number of interactions, and their types between the ligand and protein_DNA complex. حسب Ahmed A. Gaber (13302308)

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Binding of compound 17 with DNA-Topo II complex. حسب Ahmed A. Gaber (13302308)

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Effect of compound 16 on the levels of BAX, and Bcl-2 proteins expression in HCT-116 cells treated for48 h. حسب Ahmed A. Gaber (13302308)

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Effect of compound 16 on cell cycle progression in HCT-116 cells after 48h treatment. حسب Ahmed A. Gaber (13302308)

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Fig 4 - حسب Ahmed A. Gaber (13302308)

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