Chronic colitis induces marked changes in protein expression in the adult heart and blood. by Yanbo Tang (11457519)

Cinacalcet administered early in the inactive phase markedly decrease parathyroid Ki-67 index. by Søren Egstrand (10906087)

The parameters of gas exchange markedly decreased in maize <i>zmstomagen1/2</i> mutant compared with in wild type (WT). by Juan-Juan Xu (18590868)

Region-specific gain and loss of repressive marks in aged somatic tissues. by Cheng-Lin Li (3620321)

PLB is a target gene of miRNA 221. by Hongyu Li (1332669)

General procedure for the synthesis of the target compounds 11a,b,15a,b. by Ahmed A. Gaber (13302308)

Subjects:

Deletion of microglial NKCC1 markedly impacts on baseline cell morphology and alters transformation to reactive microglia. by Krisztina Tóth (12009827)

“…(<b>C)</b> NKCC1 mRNA levels in isolated NKCC1 KO microglia was markedly reduced in comparison to WT cells. (<b>D, E)</b> NKCC1 protein expression in a large number of randomly sampled NKCC1 KO microglia cells is markedly reduced compared to WT cells. …”

<i>RTTN</i>-mutated organoids exhibit decreased proliferation and increased cell death at early stages. by Justine Guguin (9088672)

Pericentric heterochromatin structural integrity is disrupted in the absence of CFDP1 due to loss of core heterochromatin protein, HP1α and H3K9me3 marks. by Gokul Gopinathan (7930679)

miRNA 221 alleviated calcium overload in myocardium and inhibited the expression of apoptosis-related genes in MIRI mice. by Hongyu Li (1332669)

Altered expression of genes related to Ca²⁺ cycling or myocardial contraction. by Hongyu Li (1332669)

miRNA 221 alleviated myocardial injury and inhibited apoptosis and necrosis of cardiac cells in MIRI mice. by Hongyu Li (1332669)

miRNA 221 improved left ventricular contractile function in MIRI mice. by Hongyu Li (1332669)

Nemp1 KO mice display increased splenic stress erythropoiesis. by Didier Hodzic (132944)

<b>Effects of marked weight loss induced by gastric bypass surgery or low-calorie diet alone on postprandial glucose disposal in type 2 diabetes</b> by Bettina Mittendorfer (88840)

“…<p dir="ltr">We used a dual (intravenous and oral) glucose tracer protocol to evaluate rates of glucose appearance into the circulation, insulin-mediated glucose disposal (IMGD), and non-insulin-mediated glucose disposal (NIMGD) for four hours after consumption of a mixed meal in people with obesity and type 2 diabetes before and after marked (~20%) weight loss, induced by behavioral diet therapy (BDT, n=11) or Roux-en-Y gastric bypass (RYGB) surgery (n=9).…”

General procedures for the synthesis of the key compounds 7a, b, 9, and 10. by Ahmed A. Gaber (13302308)

Subjects:

Electron micrograph of the Langerhans islet of the monkey before and after the hydroxynonenal injections. by Piyakarn Boontem (11663090)

Subjects:

Binding of compound 12b with DNA-Topo II complex. by Ahmed A. Gaber (13302308)

Subjects:

Binding of compound 11a with DNA-Topo II complex. by Ahmed A. Gaber (13302308)

Subjects:

The proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases in <i>APC</i>-mutant colon tissues from FAP patients. by Tao Zhang (43681)

“…In contrast, in <i>APC</i>-mutant tissues from FAP patients, the proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases. Crypt cell levels are indicated that range from crypt bottom (level 1) to crypt top (level ~82). …”