Implementing CYP2C19 Pharmacogenetic Testing for Personalized Antiplatelet Therapy: Findings From the QPGx-CARES Initiative حسب Rania Abdel-latif (18295396)

"…<h3 dir="ltr">Purpose</h3><p dir="ltr">CYP2C19 loss-of-function (LoF) alleles are associated with increased cardiovascular risk in clopidogrel-treated percutaneous coronary intervention (PCI) patients. …"

Exercise training-induced speeding of VO₂kinetics is not intensity domain-specific or correlated with indices of exercise performance حسب Erin Calaine Inglis (7042334)

"…Training participants completed two three-week phases of three supervised sessions per week, with physiological evaluations performed at PRE, MID and POST intervention. …"

Top Concerns of Tweeters During the COVID-19 Pandemic: Infoveillance Study حسب Alaa Abd-Alrazaq (17430900)

"…The mean sentiment was positive for 10 topics and negative for 2 topics (deaths caused by COVID-19 and increased racism). The mean for tweet topics of account followers ranged from 2722 (increased racism) to 13,413 (economic losses). …"

Regulation of circulating CTRP-2/CTRP-9 and GDF-8/GDF-15 by intralipids and insulin in healthy control and polycystic ovary syndrome women following chronic exercise training حسب Jayakumar Jerobin (6595520)

"…</p> <h2>Results</h2> <p>Intralipids dramatically increased CTRP-2 levels in PCOS (P = 0.02) and control (P = 0.004) subjects, which was not affected by insulin infusion or by exercise. …"

Durability of Cardiometabolic Outcomes Among Adolescents After Sleeve Gastrectomy: First Study with 9-Year Follow-up حسب Wahiba Elhag (5245547)

"…</p> <h2>Results</h2> <p>Follow-up rates were 57.53%, 82.87%, 85.24%, 83.92%, and 83.33% at the five time points. The preoperative mean body mass index (BMI) (45.60 ± 6.50 kg/m2) decreased at year 1 (30.04 ± 4.96 kg/m2, P=0.001) and was maintained up to 9 years (30.20 ± 3.92 kg/m2, P = 0.001). …"

10-Day structured initiation protocol from multiple daily injection to hybrid closed-loop system in children and adolescents with type 1 diabetes حسب Goran Petrovski (129836)

"…The participants used the sensor for a median of 92% of the time and spent a median of 89% in Auto Mode. The mean HbA1c decreased from 8.2 ± 1.4% (66 ± 15.3 mmol/mol) at baseline to 6.7 ± 0.5% (50 ± 5.5 mmol/mol) at the end of the study (p = 0.017). …"

Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills حسب Tariq Abbas (368053)

"…However, EMG measurements showed significant reductions in average EMG power, total time, dominant frequency, and cumulative muscle workload after training. Additionally, the mean power spectral density of the EMG signal decreased notably post-training. …"

Peripheral inflammatory and metabolic markers as potential biomarkers in treatment-resistant schizophrenia: Insights from a Qatari Cohort حسب Mohamed Adil Shah Khoodoruth (14589828)

"…Multivariate analysis highlighted significant differences in platelet count, mean platelet volume (MPV), TG, HbA1c, BMI, neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR), and ferritin among the groups. …"

Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers حسب Yadav, Santosh K.

"…Decreased FA along with both increased and decreased MD in different brain regions was present in HUC compared to CHNM. …"
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HIV epidemiology among female sex workers and their clients in the Middle East and North Africa: systematic review, meta-analyses, and meta-regressions حسب Hiam Chemaitelly (439114)

"…There was strong evidence for increasing prevalence post-2003; the odds increased by 15% per year (AOR = 1.15, 95% CI = 1.09–1.21). …"

A Modification to Enhance the Survival of the Island FDMA Flap by Adding a Skin Bridge حسب Salim Al Lahham (16515333)

"…</p><h3>Conclusion</h3><p dir="ltr">FDMA is one of the best choices when it comes to distal thumb reconstruction, but it has the disadvantage of distal necrosis, which might be avoided when using the technique mentioned in this study.…"

Removal of Benzene and Toluene from Synthetic Wastewater by Adsorption onto Magnetic Zeolitic Imidazole Framework Nanocomposites حسب George Z. Kyzas (740387)

"…Our conducted experiments introduced the neutral pH as the best pH range to obtain the maximum removal. Fitting the adsorption data into the various models revealed the aptness of the Langmuir isotherm equation in describing experimental information and highest adsorption capacity; for benzene it was 129.4, 134.2, 137.3, and 148.2 mg g⁻¹, but for toluene it was 118.4, 125.2, 129.6, and 133.1 mg g⁻¹, for temperature 20, 30, 40, and 50 °C, respectively. …"

CRISPR-Cas Controls Cryptic Prophages حسب Sooyeon Song (4891132)

"…<div><p>The bacterial archetypal adaptive immune system, CRISPR-Cas, is thought to be repressed in the best-studied bacterium, Escherichia coli K-12. We show here that the E. coli CRISPR-Cas system is active and serves to inhibit its nine defective (i.e., cryptic) prophages. …"

Impact of Exclusive Bus Lanes on Traffic Performance in Urban Areas حسب Abdulwahid, Amro Riyadh

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Zirconium Silicate/IL/Mxene-based composite membranes for high-temperature fuel cell applications حسب Edwin, Reeves Nayagam

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Comparing WZB117-liposome Synthesis via Thin-film Hydration and Microfluidic Methods حسب Yaramiree, Atena

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Methylomic profiling in trisomy 21 identifies cognition- and Alzheimer’s disease-related dysregulation حسب Larissa Haertle (3864310)

HIV incidence among people who inject drugs in the Middle East and North Africa: mathematical modelling analysis حسب Ghina R Mumtaz (18629722)

"…</p><h3>Results</h3><p dir="ltr">The estimated HIV incidence rate for 2017 among PWID ranged between 0.7% per person‐year (ppy) in Tunisia and 7.8% ppy in Pakistan, with Libya being an outlier (24.8% ppy). …"

Public motives and willingness to participate in first-in-human clinical trials in Saudi Arabia: A new era in the making حسب Almutairi, Adel F.

"…Results Study participants who were invited and completed the survey were 657. The percentage mean score of participants’ attitudes and concern was 70.1 ± 16.4 and 58.3 ± 15.3 respectively. …"
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Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 حسب Stein Emil, Vollset

"…Forecasts for the reference scenario found that health will improve in the coming decades, with all-cause age-standardised DALY rates decreasing in every GBD super-region. The total DALY burden measured in counts, however, will increase in every super-region, largely a function of population ageing and growth. …"
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