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Image_1_Multi-Component Comparative Pharmacokinetics in Rats After Oral Administration of Fructus aurantii Extract, Naringin, Neohesperidin, and Naringin-Neohesperidin.pdf
Published 2020“…There were significant differences in pharmacokinetic parameters for naringenin and hesperetin between the compatibility, FA extract group vs monomer group: ① remarkable increases in the values of AUC<sub>(0–∞)</sub>, AUC<sub>(0–t)</sub> and C<sub>max</sub>; ② obvious decrease of CL<sub>Z/F</sub>; and ③ longer t<sub>max</sub> and t<sub>1/2z</sub>. …”
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Table_1_Multi-Component Comparative Pharmacokinetics in Rats After Oral Administration of Fructus aurantii Extract, Naringin, Neohesperidin, and Naringin-Neohesperidin.docx
Published 2020“…There were significant differences in pharmacokinetic parameters for naringenin and hesperetin between the compatibility, FA extract group vs monomer group: ① remarkable increases in the values of AUC<sub>(0–∞)</sub>, AUC<sub>(0–t)</sub> and C<sub>max</sub>; ② obvious decrease of CL<sub>Z/F</sub>; and ③ longer t<sub>max</sub> and t<sub>1/2z</sub>. …”
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Table_2_Multi-Component Comparative Pharmacokinetics in Rats After Oral Administration of Fructus aurantii Extract, Naringin, Neohesperidin, and Naringin-Neohesperidin.docx
Published 2020“…There were significant differences in pharmacokinetic parameters for naringenin and hesperetin between the compatibility, FA extract group vs monomer group: ① remarkable increases in the values of AUC<sub>(0–∞)</sub>, AUC<sub>(0–t)</sub> and C<sub>max</sub>; ② obvious decrease of CL<sub>Z/F</sub>; and ③ longer t<sub>max</sub> and t<sub>1/2z</sub>. …”