PPM1A facilitates both nuclear distribution and transcription potency of YAP/TAZ. حسب Ruyuan Zhou (10197187)

"…Dox, doxycycline; LATS1, large tumor suppressor kinase 1; MST1, mammalian sterile 20-like kinase 1; PPM1A, protein phosphatase magnesium-dependent 1A; TAZ, transcriptional coactivator with PDZ-binding motif; TEAD, transcriptional enhanced associate domain; WT, wild-type; YAP, Yes-associated protein.…"

Deletion of microglial NKCC1 markedly impacts on baseline cell morphology and alters transformation to reactive microglia. حسب Krisztina Tóth (12009827)

Table_1_Positive Allosteric Modulation of CD11b as a Novel Therapeutic Strategy Against Lung Cancer.DOCX حسب Terese Geraghty (8873387)

"…The profiling also showed a significant decrease in CCL2 levels and a concomitant reduction in Ly6C^hi monocytes in circulation in both groups. …"

Table_2_Positive Allosteric Modulation of CD11b as a Novel Therapeutic Strategy Against Lung Cancer.DOCX حسب Terese Geraghty (8873387)

"…The profiling also showed a significant decrease in CCL2 levels and a concomitant reduction in Ly6C^hi monocytes in circulation in both groups. …"

Image_3_Positive Allosteric Modulation of CD11b as a Novel Therapeutic Strategy Against Lung Cancer.TIFF حسب Terese Geraghty (8873387)

"…The profiling also showed a significant decrease in CCL2 levels and a concomitant reduction in Ly6C^hi monocytes in circulation in both groups. …"

Image_1_Positive Allosteric Modulation of CD11b as a Novel Therapeutic Strategy Against Lung Cancer.TIFF حسب Terese Geraghty (8873387)

"…The profiling also showed a significant decrease in CCL2 levels and a concomitant reduction in Ly6C^hi monocytes in circulation in both groups. …"

Image_2_Positive Allosteric Modulation of CD11b as a Novel Therapeutic Strategy Against Lung Cancer.TIFF حسب Terese Geraghty (8873387)

"…The profiling also showed a significant decrease in CCL2 levels and a concomitant reduction in Ly6C^hi monocytes in circulation in both groups. …"

Pearson clusters and fPCA considering all protein-coding genes. حسب Leo Zeitler (13775500)

Image_4_Astrocytic Ephrin-B1 Controls Synapse Formation in the Hippocampus During Learning and Memory.TIF حسب Amanda Q. Nguyen (8584413)

"…The goal of this study was to understand the mechanism by which astrocytic ephrin-B1 influences learning; specifically, learning-induced remodeling of synapses and dendritic spines in CA1 hippocampus using fear-conditioning paradigm. While we found a higher dendritic spine density and clustering on c-Fos-positive (+) neurons activated during contextual memory recall in both wild-type (WT) and KO mice, overall spine density and mEPSC amplitude were increased in CA1 neurons of KO compared to WT. …"

Data_Sheet_1_Astrocytic Ephrin-B1 Controls Synapse Formation in the Hippocampus During Learning and Memory.docx حسب Amanda Q. Nguyen (8584413)

"…The goal of this study was to understand the mechanism by which astrocytic ephrin-B1 influences learning; specifically, learning-induced remodeling of synapses and dendritic spines in CA1 hippocampus using fear-conditioning paradigm. While we found a higher dendritic spine density and clustering on c-Fos-positive (+) neurons activated during contextual memory recall in both wild-type (WT) and KO mice, overall spine density and mEPSC amplitude were increased in CA1 neurons of KO compared to WT. …"

Image_3_Astrocytic Ephrin-B1 Controls Synapse Formation in the Hippocampus During Learning and Memory.TIF حسب Amanda Q. Nguyen (8584413)

"…The goal of this study was to understand the mechanism by which astrocytic ephrin-B1 influences learning; specifically, learning-induced remodeling of synapses and dendritic spines in CA1 hippocampus using fear-conditioning paradigm. While we found a higher dendritic spine density and clustering on c-Fos-positive (+) neurons activated during contextual memory recall in both wild-type (WT) and KO mice, overall spine density and mEPSC amplitude were increased in CA1 neurons of KO compared to WT. …"

Image_1_Astrocytic Ephrin-B1 Controls Synapse Formation in the Hippocampus During Learning and Memory.TIF حسب Amanda Q. Nguyen (8584413)

"…The goal of this study was to understand the mechanism by which astrocytic ephrin-B1 influences learning; specifically, learning-induced remodeling of synapses and dendritic spines in CA1 hippocampus using fear-conditioning paradigm. While we found a higher dendritic spine density and clustering on c-Fos-positive (+) neurons activated during contextual memory recall in both wild-type (WT) and KO mice, overall spine density and mEPSC amplitude were increased in CA1 neurons of KO compared to WT. …"

Image_2_Astrocytic Ephrin-B1 Controls Synapse Formation in the Hippocampus During Learning and Memory.TIF حسب Amanda Q. Nguyen (8584413)

"…The goal of this study was to understand the mechanism by which astrocytic ephrin-B1 influences learning; specifically, learning-induced remodeling of synapses and dendritic spines in CA1 hippocampus using fear-conditioning paradigm. While we found a higher dendritic spine density and clustering on c-Fos-positive (+) neurons activated during contextual memory recall in both wild-type (WT) and KO mice, overall spine density and mEPSC amplitude were increased in CA1 neurons of KO compared to WT. …"

DataSheet_1_Cryptococcus neoformans Δsgl1 Vaccination Requires Either CD4+ or CD8+ T Cells for Complete Host Protection.pdf حسب Tyler G. Normile (11405684)

"…Th1 cytokines increased whereas Th2 cytokines concurrently decreased, coinciding with a large recruitment of leukocytes to the lungs. …"

Abnormal social communication and mounting in Katnal2-KO mice. حسب Ryeonghwa Kang (6793046)

"…(<i>n</i> = 11 pairs [WT], 13 [KO], two-way RM-ANOVA). (C) Normal levels of social interaction in Katnal2-KO mice (2–3 months) in a modified version of the direct social interaction test, where a subject mouse interacted with a stranger mouse of C3H background (i.e., with a different coat color) and unidirectional and bidirectional/reciprocal social interactions were measured. …"

Microglial autophagy defect causes parkinson disease-like symptoms by accelerating inflammasome activation in mice حسب Jinbo Cheng (712740)

"…Inhibition of NLRP3 inflammasome activation by administration of MCC950, a specific inhibitor for NLRP3, decreased MIF expression and neuroinflammatory levels, and rescued the loss of TH neurons in the substantial nigra (SN). …"

DataSheet_1_Dysregulated hepatic lipid metabolism and gut microbiota associated with early-stage NAFLD in ASPP2-deficiency mice.docx حسب Fang Xie (103933)

"…The levels of hepatic long chain omega-3 fatty acid, eicosapentaenoic (EPA, 20:5 n-3) and docosahexaenoic (DHA, 22:6 n-3), were decreased at day 10 and increased at day 40 in ASPP^+/- mice. …"

Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis حسب Shaogui Wang (310181)

Supporting data for "Mechanistic study of TSPYL2 stabilization in <i>TSPYL1 </i>depleted cells" حسب Xu Luo (12992484)

"…In this study, the treatment of USP7 inhibitor HBX 41108 increased the level of TSPYL2 and decreased the level of the ubiquitin ligase including NEDD4L and MDM2. …"

The regulation of AsfR on tmRNA expression mediates bacterial motility and virulence حسب Huimin Chang (21142907)

"…Consistently, the transcription level of tmRNA was significantly decreased in Δ<i>asfR</i> compared with WT of <i>A. veronii </i>by quantitative real-time PCR (RT-qPCR) analyses. …"