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Spatial information is significantly decreased in dCA1 and vCA1 in APP/PS1 mice.
Published 2024“…The spatial information in dCA1 was significantly larger than circularly shuffled spike trains with similar mean firing rates for C57BL/6 mice (mean ± std: empirical = 0.132 ± 0.048, shuffled = 0.124 ± 0.035, p < 0.001, two-sided Wilcoxon rank-sum test, n<sub>empirical</sub> = 305 units from 5 recording sessions, n<sub>shuffled</sub> = 30500 simulated units from 5 recording sessions), but not for APP/PS1 mice (mean ± std: empirical = 0.128 ± 0.051, shuffled = 0.123 ± .047, p = 0.39, two-sided Wilcoxon rank-sum test, n<sub>empirical</sub> = 180 units from 4 recording sessions, n<sub>shuffled</sub> = 18000 simulated units from 4 recording sessions). …”
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Spatial information of excitatory neurons in APP/PS1 mice are decreased in dCA1 and vCA1.
Published 2024“…<p>(A) In dCA1, spatial information was decreased in APP/PS1 mice relative to C57BL/6 controls (mean ± std: C57BL/6 = 0.134 ± 0.050, APP/PS1 = 0.132 ± 0.054, p < 0.01, two-sided Wilcoxon rank-sum test, n<sub>C57BL/6</sub> = 229 units from 5 recording sessions, n<sub>APP/PS1</sub> = 124 units from 4 recording sessions). …”
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Supplementary Material for: Tea Consumption Is Associated with Decreased Disease Activity of Rheumatoid Arthritis in a Real-World, Large-Scale Study
Published 2020“…<b><i>Objectives:</i></b> The aim of this study was to explore the possible association of tea consumption with RA through a large-scale, real-world study. …”
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<b>Supporting data for manuscript</b> "<b>Voluntary locomotion induces an early and remote hemodynamic decrease in the large cerebral veins</b>"
Published 2025“…<p dir="ltr">The CSV file 'Eyreetal_DrainingVein_SourceData' contains the averaged time series traces and extracted metrics from individual experiments used across Figures 1-5 in the manuscript "Voluntary locomotion induces an early and remote hemodynamic decrease in the large cerebral veins". The following acronyms included in the CSV file are defined as follows: Hbt is total hemoglobin, Art is artery region, DV is draining vein region, WV is whisker vein region, SEM is standard error mean, TS is time series, max peak is maximum peak, min peak is minima, AUC is area under the curve, WT is wild-type, AD is Alzheimer's disease, ATH is atherosclerosis and MIX is mixed AD/atherosclerosis. …”
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In superadditive networks, more enhancers decrease noise and fidelity.
Published 2023“…<p>(A) Superadditivity is implemented in our model by linearly increasing <i>k</i><sub>on</sub> rates and linearly decreasing <i>k</i><sub>off</sub> rates. …”
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Performance of the response detection algorithm at detecting simulated increases versus decreases in firing rate.
Published 2020“…<p>Curves reflect the mean (±SD) fraction of increases and decreases detected as a function of the simulated response size (expressed as percent of baseline firing rate). …”
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Triple B←N Lewis Pair-Functionalized Triazatruxenes with Large Stokes Shifts
Published 2023Subjects: -
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