Mean(SD) AUC-ROC for Study Population and Demographic Subgroups by Classification Algorithm. by Elizabeth A. Campbell (3019293)

Subjects:

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

The PRAME-AS knockout cells showed a decrease in migration, proliferation, stemness, and viability. by Zahra Hosseininia (22265113)

Percentage decrease in model output peak with the administration of exogenous estrogen/progesterone. by Brenda Lyn A. Gavina (15285185)

Dramatic Lockdown Fossil Fuel CO₂ Decrease Detected by Citizen Science-Supported Atmospheric Radiocarbon Observations by Jocelyn C. Turnbull (6083705)

Schematic of Large-Scale Filtration System (LSFS). by Haedi E. DeAngelis (10652168)

Fig 3 - by Claire Gauquelin Des Pallieres (15333248)

Δ ROC AUC values obtained with NMM by the addition of various biomarker combinations to the clinical data (participant demographics, clinical assessments, and cognitive assessments... by Batuhan K. Karaman (14129223)

Large Decreases in Tailpipe Criteria Pollutant Emissions from the U.S. Light-Duty Vehicle Fleet Expected in 2020–2040 by Rachael H. Dolan (17918706)

“…Reductions in CO₂ emissions follow a similar pattern. Large decreases in criteria pollutant and CO₂ emissions from light duty vehicles lie ahead.…”

Large Decreases in Tailpipe Criteria Pollutant Emissions from the U.S. Light-Duty Vehicle Fleet Expected in 2020–2040 by Rachael H. Dolan (17918706)

“…Reductions in CO₂ emissions follow a similar pattern. Large decreases in criteria pollutant and CO₂ emissions from light duty vehicles lie ahead.…”

SHAP Value Analysis for Model Prediction. by Youli Jiang (15249070)

Subjects:

Large direct shear test system. by Changbo Du (14014481)

Entropy analysis for the large data set including the GST dataset. by Aleksi Sutinen (10039145)

Data from: Colony losses of stingless bees increase in agricultural areas, but decrease in forested areas by Malena Sibaja Leyton (18400983)

Differential expression analysis of nuclear transcripts after siAPOBEC3A depletion reveals induction of TP53 targets and decreases in cell cycle and cell growth regulator transcrip... by Mason A. McCool (11889842)

The burden of COVID-19 and anomie are associated with a decreased system support and increased extreme discontent but not with changes in social solidarity. by Alexander Bor (10932496)

Activating cAMP synthesis decreases liberation of propionyl-CoA from cholesterol. by Kaley M. Wilburn (12060476)

Increasing gaps and decreasing returns attenuate spending effects. by William Minozzi (8564712)

Comparison of ROCs/AUCs of the HpAfr-ELISA assay at three repeated testing. by Evariste Tshibangu-Kabamba (11414297)