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The proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases in <i>APC</i>-mutant colon tissues from FAP patients.
Published 2020“…In contrast, in <i>APC</i>-mutant tissues from FAP patients, the proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases. Crypt cell levels are indicated that range from crypt bottom (level 1) to crypt top (level ~82). …”
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General procedures for the synthesis of the key compounds 7a, b, 9, and 10.
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The contributions of amino acids around 10 Å of the ligand to the binding free energy.
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Effect of compound 16 on stages of the cell death process in HCT-116 cells after 48 h treatment.
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