Impaired Ubr5 function results in increased canonical and decreased non-canonical HH signalling. by David Mellis (2833469)

“…<p>Immunohistochemical analysis of six-week-old control and <i>Ubr5</i>^<i>mt</i> tibial AC examined for markers of canonical HH pathway activity. Relative to (A, C) control, (B, D) <i>Ubr5</i>^<i>mt</i> AC displayed increased staining intensities for PTCH1 (A, B) and GLI1 (C, D) with GLI1 exhibiting expanded expression domains (D, double-headed arrows). …”

<i>Ubr5</i>^<i>mt</i> synovium exhibits markers of increased canonical and decreased non-canonical HH signalling. by David Mellis (2833469)

<i>RTTN</i>-mutated organoids exhibit decreased proliferation and increased cell death at early stages. by Justine Guguin (9088672)

BA attenuated the decrease in the expression of ZO-1 and Occludin induced by LPS in Caco2 cells. by Luqiong Liu (11537092)

IGF-1 does not increase collagen in males. by Patricia Snarski (22305205)

Long-range chromosomal interactions increase and mark repressed gene expression during adipogenesis by Kristina M. Garske (11220178)

“…In summary, we identify LRIs that mark repressed regions of the genome, and these interactions increase across adipogenesis, pinpointing developmental regions that need to be repressed in a cell-type specific way for adipogenesis to proceed.…”

Variable importance plot (mean decrease accuracy and mean decrease Gini). by Fernando Martinez-Taboada (8655132)

Fig 5 Data. by Kevin D. Gaitonde (15411707)

Subjects:

The proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases in <i>APC</i>-mutant colon tissues from FAP patients. by Tao Zhang (43681)

“…<p>Representative IHC stains of normal, normal-appearing FAP, and FAP adenomatous colonic crypts are shown for the expression of the: <b>(A)</b> NEC marker chromogranin-A (CGA). <b>(B)</b> SC marker ALDH1. …”

Fig 2A–2C and 2G–2L Data. by Kevin D. Gaitonde (15411707)

Subjects:

GXM decreases the trans-endothelial electrical resistance (TEER) and transmigration of <i>C</i>. <i>neoformans</i> through HBECs in a blood brain barrier (BBB) model. by Hiu Ham Lee (15374677)

The analyses of TCGA transcriptome data indicated that an increased expression of SPRR1A predicts a poor prognosis in PDAC patients. by Kohei Yamakawa (3523370)

Subjects:

Immunohistochemical analysis of p-Akt expression in various experimental groups showing negative expression in control group, marked increased expression along the extended fibrous... by Rehab F. Abdel-Rahman (11886404)

Y-27632 collaborated with BA to attenuate the increase in the integrity and decrease in the permeability of epithelial barrier injury induced by LPS in Caco2 monolayers. by Luqiong Liu (11537092)

Y-27632 synergized with BA to alleviate the decrease in the expression of and abnormal localization of ZO-1 and Occludin in LPS-induced Caco2 cells. by Luqiong Liu (11537092)

ALS patients’ tissues exhibit increased phosphorylation of MARK2. by Yu-Ning Lu (10291271)

“…Increased phosphorylation of MARK2-⁵⁹⁵T is observed in all ALS patient tissues. …”

IGF-1 increases collagen in mice with myeloid MMP8 reintroduction. by Patricia Snarski (22305205)

Regenerating axons are increased by ATRA and decreased by clodronate. by Valeria De La Rosa-Reyes (6658613)

Fibrosis markers. by Dwight D. Harris (14484648)

The effect of HA digestion and HA replenishment alone or with CS on barrier function measured by TEER. by Charlotte J. van Ginkel (20790466)

“…PS decreased TEER. (C) Different treatments (treatment groups n = 8)with HA and/or CS did not affect TEER recovery after PS treatment, full recovery was seen in all groups after 24 hours. …”