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The proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases in <i>APC</i>-mutant colon tissues from FAP patients.
Published 2020“…In contrast, in <i>APC</i>-mutant tissues from FAP patients, the proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases. Crypt cell levels are indicated that range from crypt bottom (level 1) to crypt top (level ~82). …”
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ALS patients’ tissues exhibit increased phosphorylation of MARK2.
Published 2021“…Increased phosphorylation of MARK2-<sup>595</sup>T is observed in all ALS patient tissues. …”
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Deletion of Hhp2 markedly increased Sre1 activity.
Published 2020“…<p>Deletion of <i>hhp2</i><sup>+</sup> gene markedly increased Sre1 activity in the presence/absence of CLZ (2 μg/ml to 8 μg/ml) (A), TER (2 μg/ml to 8 μg/ml) (B) or CoCl<sub>2</sub> (0.08 mM to 0.32 mM) (C). …”
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Fig 2A–2C and 2G–2L Data.
Published 2023“…We observed a marked decrease in nocturnal locomotion of <i>Opn5</i><sup><i>cre</i></sup><i>; Gnas</i><sup><i>fl/fl</i></sup> mice at both 28°C and 22°C, but no overall differences in energy expenditure, respiratory exchange, or food and water consumption. …”
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Evogliptin attenuates the pyroptotic cell death of VSMCs during CER treatment by decreasing the pyroptotic-associated genes and GSDM-D cleavage efficiency <i>in-vitro.</i>
Published 2025“…<p>(A) Bar graph showed EVO significantly decreased Lactate dehydrogenase (LDH) release in CER treated P<sub>i</sub>‐induced VSMCs. …”
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Increased phosphorylation of MARK2 occurs in the affected tissues of a mutant SOD1-induced ALS mouse model.
Published 2021“…The staining of phosphorylated MARK2-<sup>595</sup>T in all 3 brain regions is increased in the SOD1<sup>G93A</sup> mice as compared to NTg mice. …”
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