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The large subunit of TFIIF, Tfg1, is sumoylated at Lys 60/61.
Published 2021“…<p><b>(A)</b> Yeast strains were generated that each express a 6xHA C-terminal epitope tag on a different GTF subunit, including Toa1 (TFIIA), Taf7 (TFIID), Taf8 (TFIID), Tfg1 (TFIIF), or Tfa1 (TFIIE). Cultures of the strains were used to prepare lysates, under non-denaturing conditions, that were then used in HA IP experiments, followed by SUMO and HA immunoblots (IBs). …”
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DataSheet_1_Increased tumor glycolysis is associated with decreased immune infiltration across human solid tumors.zip
Published 2022“…<p>Response to immunotherapy across multiple cancer types is approximately 25%, with some tumor types showing increased response rates compared to others (i.e. response rates in melanoma and non-small cell lung cancer (NSCLC) are typically 30-60%). …”
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