بدائل البحث:
largest decrease » largest decreases (توسيع البحث), marked decrease (توسيع البحث)
larger decrease » marked decrease (توسيع البحث)
ct largest » _ largest (توسيع البحث)
ct larger » _ larger (توسيع البحث), c large (توسيع البحث)
can also » may also (توسيع البحث)
largest decrease » largest decreases (توسيع البحث), marked decrease (توسيع البحث)
larger decrease » marked decrease (توسيع البحث)
ct largest » _ largest (توسيع البحث)
ct larger » _ larger (توسيع البحث), c large (توسيع البحث)
can also » may also (توسيع البحث)
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Paradoxical Increase of Permeability and Lipophilicity with the Increasing Topological Polar Surface Area within a Series of PRMT5 Inhibitors
منشور في 2022"…HBA moment was subsequently deployed as a design parameter leading to the discovery of inhibitors with not only improved passive permeability but also reduced P-glycoprotein (P-gp) transport. Our case study suggests that hidden polarity as quantified by TPSA-3DPSA can be rationally designed through QM calculations.…"
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Paradoxical Increase of Permeability and Lipophilicity with the Increasing Topological Polar Surface Area within a Series of PRMT5 Inhibitors
منشور في 2022"…HBA moment was subsequently deployed as a design parameter leading to the discovery of inhibitors with not only improved passive permeability but also reduced P-glycoprotein (P-gp) transport. Our case study suggests that hidden polarity as quantified by TPSA-3DPSA can be rationally designed through QM calculations.…"
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Paradoxical Increase of Permeability and Lipophilicity with the Increasing Topological Polar Surface Area within a Series of PRMT5 Inhibitors
منشور في 2022"…HBA moment was subsequently deployed as a design parameter leading to the discovery of inhibitors with not only improved passive permeability but also reduced P-glycoprotein (P-gp) transport. Our case study suggests that hidden polarity as quantified by TPSA-3DPSA can be rationally designed through QM calculations.…"
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Paradoxical Increase of Permeability and Lipophilicity with the Increasing Topological Polar Surface Area within a Series of PRMT5 Inhibitors
منشور في 2022"…HBA moment was subsequently deployed as a design parameter leading to the discovery of inhibitors with not only improved passive permeability but also reduced P-glycoprotein (P-gp) transport. Our case study suggests that hidden polarity as quantified by TPSA-3DPSA can be rationally designed through QM calculations.…"
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Camellia japonica CT slice images
منشور في 2024"…The 3D segmentation results were also obtained and visualized successfully.</p><p dir="ltr">The authors would like to thank Suzuki and Ohtake Laboratory, Graduate School of Engineering, University of Tokyo, for CT data acquisition for this study.…"
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