Increased Levels of Circulating and Tumor-Infiltrating Granulocytic Myeloid Cells in Colorectal Cancer Patients by Salman M. Toor (8854751)

“…<p dir="ltr">Increased levels of myeloid cells, especially myeloid-derived suppressor cells (MDSCs), have been reported to correlate with bad prognosis and reduced survival in cancer patients. …”

Immune Checkpoints in Circulating and Tumor-Infiltrating CD4+ T Cell Subsets in Colorectal Cancer Patients by Salman M. Toor (8854751)

“…We found a significant increase in the levels of CD4⁺FoxP3⁺Helios⁺ T cells, which represent potentially highly immunosuppressive Tregs, in the CRC TME. …”

Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59 by Ramada R. Khaswaneh (22224544)

“…Preserving the level of Factor H and CD59 in MSCs has significant clinical implication to increase their retention rate in hypoxic conditions and prolong their survival.…”

Circulating and Tumor-Infiltrating Immune Checkpoint-Expressing CD8+ Treg/T Cell Subsets and Their Associations with Disease-Free Survival in Colorectal Cancer Patients by Alhasan Alsalman (14802873)

“…We investigated the expression levels of key immune checkpoints (ICs) and Treg-related markers in CD8+ T cells. …”

The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) by Varghese P. Inchakalody (14557382)

“…Bisulfite-sequencing demonstrated 45.6% demethylation efficiency at the NY-ESO-1 gene promoter region and RT-qPCR analysis confirmed the significant induction of NY-ESO-1 at mRNA level (128-fold increase, *p < 0.050). We then investigated the mechanism by which 5-Aza-CdR inhibits cell proliferation in the NCI–H1975 cell line. …”

Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 by Olfa Khalifa (10914452)

“…Interestingly, knocking down MALAT1 significantly reduces the expression of CD36 in steatosis HepG2 cells in the presence of Ex-4. …”

Highly sensitive humidity sensor based on cadmium selenide quantum dots-polymer composites: synthesis, characterization, and effect of UV/ozone treatment by Khouloud Jlassi (2583832)

“…The sensor's sensitivity is improved with increasing UV radiation exposure. The electrical response of the PVDF-CdSe humidity sensors after 30 min of UV/ozone treatment reveals that at higher humidity levels (i.e., > 80% RH), the sensors exhibit an irregular response. …”

A novel approach to reduce spurious switching activity in high-level synthesis. (c2009) by Aaraj (El), Elie

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Novel Whole-Cell Inactivated Neisseria Gonorrhoeae Microparticles as Vaccine Formulation in Microneedle-Based Transdermal Immunization by Rikhav Gala (18069364)

“…Significant increase in antigen-specific IgG antibody levels was observed at the end of week 2 in groups that received the vaccine compared to the group receiving empty nanoparticles. …”

Response of cauliflower (<i>Brassica oleracea</i> L.) to nitric oxide application under cadmium stress by Jing Ma (24574)

“…The concentration of malondialdehyde (MDA) and Cd accumulation (roots and shoots) increased significantly (P < 0.05) under the increasing levels of Cd in all genotypes of B. oleracea while antioxidant (enzymatic or non-enzymatic) capacity and nutritional status of the plants was decreased with varying levels of Cd in the sand. …”

Risk Factors for Post-Cesarean, Surgical Site Infections in a Multi-Ethnic Population of Qatar by Sufia Athar (14777830)

“…In our hospital, the SSIs after CD were noted to increase in 2016 and first quarter of 2017. …”

Evaluation of heavy metals content in dietary supplements in Lebanon by Korfali, Samira Ibrahim

“…Whereas, 30% of analyzed samples had levels of Cd above allowable levels, and were statistically correlated with Ca, and Zn essential minerals. …”
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Circulating exosomal immuno-oncological checkpoints and cytokines are potential biomarkers to monitor tumor response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patien... by Shayista Akbar (14442117)

“…We first confirmed the identity of the isolated exosomes to have their specific markers (CD63, CD81, HSP70 and CD91). We have demonstrated that baseline concentration of exosomal-PD-L1 (p<0.0001), exosomal-PD-L2 (p=0.0413) and exosomal-PD-1 (p=0.0131) from NSCLC patients were significantly higher than their soluble-free forms. …”

Immunoprofile of childhood diabetes by Meritxell Espino-Guarch (15430868)

“…When transcriptomic data was interrogated, an imbalance between ITGA4/ ITGB1 was observed in all groups where CD49d showed increased expression. Associated with these findings, anti-inflammatory Treg cytokines including IL-10 were decreased in T2D patients and elevated plasma levels of IL-17, which contributes to the insulin resistance and inflammation were observed.…”

Intratumoral FoxP3⁺Helios⁺ Regulatory T Cells Upregulating Immunosuppressive Molecules Are Expanded in Human Colorectal Cancer by Azharuddin Sajid Syed Khaja (19720114)

“…Levels of CD4⁺FoxP3⁺Helios⁺ Tregs were significantly increased in the TME. …”

Targeting Breast Cancer Using Hyaluronic Acid-Conjugated Liposomes Triggered with Ultrasound by Ben-Daya, Mohamed

“…HA conjugation to the liposomes resulted in a significant increase in calcein uptake by the breast cancer cell line MDA-MB-231 known for its CD44 (HA receptor) overexpression, while such an effect was not recorded with NIH-3T3, an embryonic mouse fibroblast, with low levels of CD44 expression. …”
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A novel phosphorylated STAT3 inhibitor enhances T cell cytotoxicity against melanoma through inhibition of regulatory T cells by Abou-Ghazal, Mohamed K.

“…This was confirmed by demonstrating that WP1066 inhibited FoxP3+ Treg induction in a dose-dependent manner. Moreover, CD3+ T cells exhibited markedly enhanced levels of phosphorylated ZAP-70, a critical proximal signal in T cell activation, after exposure to WP1066. …”
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Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death by Tohme, Sara

“…This involvement of ROS is confirmed with the gradual increase in intracellular ROS levels, reaching a peak at 48 hours after treatment. …”
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Identification of macrophage activation-related biomarkers in obese type 2 diabetes that may be indicative of enhanced respiratory risk in COVID-19 by Abu Saleh Md Moin (6189512)

“…Activated M2 macrophages were characterized by elevated levels of plasma CD163, TFGβ-1, MMP7 and MMP9 in OT2D. …”

yuDetecting the percent of peripheral blood mononuclear cells displaying p-STAT-3 in malignant glioma patient by Abou-Ghazal, Mohamed K.

“…Furthermore, the percent of PBMCs displaying p-STAT-3 in glioma patients was not directly correlated with the fraction of Tregs in the CD4 compartment. Conclusion: We conclude that the percent of PBMCs displaying p-STAT-3 may be increased in malignant glioma patients.…”
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